Evidence map›Paper›PMID 31804005›Full record

Trial reportDepression and anxiety2020

Changes in typical beliefs in response to complicated grief treatment.

Natalia A Skritskaya, Christine Mauro, Angel Garcia de la Garza, Franziska Meichsner, Barry Lebowitz, Charles F Reynolds, Naomi M Simon, Sidney Zisook, M Katherine Shear

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Depression and anxiety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Natalia A SkritskayaSchool of Social Work, Columbia University, New York, New York.ORCID 0000-0002-0649-5601
Christine MauroDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Angel Garcia de la GarzaDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Franziska MeichsnerDepartment of Clinical Psychology and Psychotherapy, Institute of Psychology, Goethe University, Frankfurt, Germany.
Barry LebowitzDepartment of Psychiatry, University of California San Diego and San Diego Healthcare System, San Diego, California.
Charles F ReynoldsDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Naomi M SimonDepartment of Psychiatry, NYU Langone Health, New York University School of Medicine, New York, New York.
Sidney ZisookDepartment of Psychiatry, University of California San Diego and San Diego Healthcare System, San Diego, California.ORCID 0000-0003-3341-9185
M Katherine ShearSchool of Social Work, Columbia University, New York, New York.
New York University · USUniversity of California San Diego · USGoethe University Frankfurt · DENYU Langone Health · USUniversity of Pittsburgh · US

Funding

TRAUMATIC GRIEF TREATMENT--A RANDOMIZED CONTROLLED STUDYR01MH060783 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUAN, NAIHUA, SHEAR, M KATHERINE · 2000 to 2016
$4.0M
2/4-Optimizing Treatment of Complicated GriefR01MH085308 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SIMON, NAOMI M · 2009 to 2013
$2.0M
3/4-Optimizing Complicated Grief TherapyR01MH085288 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F. · 2009 to 2013
$1.7M
4/4-Optimizing Treatment of Complicated GriefR01MH085297 · NIMH · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI ZISOOK, SIDNEY · 2009 to 2013
$1.6M
NIMH NIH HHS R01 MH060783NIMH NIH HHS R01 MH085288NIMH NIH HHS R01 MH085297NIMH NIH HHS R01 MH085308
6 · The paper itself

Abstract

backgroundProlonged grief disorder (PGD) is a new diagnosis in the 11th edition of the International Classification of Diseases, estimated to affect 1 in 10 bereaved people and causing significant distress and impairment. Maladaptive thoughts play an important role in PGD. We have previously validated the typical beliefs questionnaire (TBQ), which contains five kinds of thinking commonly seen in PGD: protesting the death, negative thoughts about the world, needing the person, less grief is wrong, and grieving too much. The current paper examines the role of maladaptive cognition as measured by the TBQ in PGD and its change with treatment.

methodsAmong participants in a multisite clinical trial including 394 adults, we examined (a) the relationship between maladaptive thoughts at baseline and treatment outcomes, (b) the relationship between maladaptive thoughts and suicidality at baseline and posttreatment, and (c) the effect of treatment with and without complicated grief therapy (CGT) on maladaptive thinking.

resultsTBQ scores were associated with treatment outcomes and were strongly related to suicidal thinking before and after treatment. TBQ scores showed significantly greater reduction in participants who received CGT with citalopram versus citalopram alone (adjusted mean standard error [SE] difference, -2.45 [0.85]; p = .004) and those who received CGT with placebo versus placebo alone (adjusted mean [SE] difference, -3.44 [0.90]; p < .001).

conclusionsMaladaptive thoughts, as measured by the TBQ, have clinical and research significance for PGD and its treatment.

Indexed as

BereavementGriefPsychotherapyCitalopramDepressionFemaleHumansInternational Classification of DiseasesMaleMiddle AgedSuicidal IdeationSurveys and QuestionnairesTreatment OutcomeCitalopramassessment/diagnosiscognitiongrief/bereavement/complicated griefsuicide/self harmtreatment

Identifiers

PMID31804005
PMCPMC6952544
OpenAlexW2992265622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.