Evidence map›Paper›PMID 31803968›Full record

ReviewAlcoholism, clinical and experimental research2020

Five Priority Areas for Improving Medications Development for Alcohol Use Disorder and Promoting Their Routine Use in Clinical Practice.

Raye Z Litten, Daniel E Falk, Megan L Ryan, Joanne Fertig, Lorenzo Leggio

Abstract readReview
In one paragraph

Review in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
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  17. Do behavioral pharmacology findings predict clinical trial outcomes? A proof-of-concept in medication development for alcohol use disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raye Z LittenNational Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.ORCID 0000-0001-7497-0809
Daniel E FalkNational Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.ORCID 0000-0002-3753-2786
Megan L RyanNational Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.
Joanne FertigNational Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.
Lorenzo LeggioSection on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0001-7284-8754

Funding

Clinical Psychoneuroendocrinology and Neuropsychopharmacology (CPN)ZIAAA000218 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI LEGGIO, LORENZO · 2013 to 2020
$22.8M
Translational Addiction MedicineZIADA000634 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LEGGIO, LORENZO · 2020 to 2021
$505k
Intramural NIH HHS Z99 DA999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alcohol DeterrentsAlcoholismAnimalsDrug DevelopmentDrug Evaluation, PreclinicalDrug IndustryHumansNational Institute on Alcohol Abuse and Alcoholism (U.S.)Precision MedicineUnited StatesAlcohol DeterrentsAlcohol Use DisorderDisseminationHealth ServicesMedicationsMedication UsePersonalized MedicineScreening ModelsTargets

Identifiers

PMID31803968
PMCPMC12434413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.