Evidence map›Paper›PMID 31803814›Full record

ArticleVirusdisease2019

Protective immunity against hepatitis B virus infection in a group of vaccinated Sri Lankan military service men following a complete course of vaccination.

Faseeha Noordeen, H M Sagara Karunaratne, Varuna Nawaratne, F N Nagoor Pitchai, S W P Lakmini Daulagala, A M S Bandara Abeykoon

Open access · greenAbstract read
In one paragraph

Article in Virusdisease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Faseeha Noordeen1Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, 20400 Sri Lanka.ORCID 0000-0002-2018-0606
H M Sagara KarunaratneFaculty of Medicine, Sir John Kotelawela Defence University, Ratmalana, 10390 Sri Lanka.
Varuna NawaratneFaculty of Medicine, Sir John Kotelawela Defence University, Ratmalana, 10390 Sri Lanka.
F N Nagoor Pitchai1Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, 20400 Sri Lanka.
S W P Lakmini Daulagala1Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, 20400 Sri Lanka.
A M S Bandara Abeykoon1Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, 20400 Sri Lanka.
University of Peradeniya · LKGeneral Sir John Kotelawala Defence University · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination is the appropriate measure to protect military personnel against the hepatitis B virus (HBV) infection. Testing the military personnel for anti-HBs levels after vaccination is vital in re-vaccinating those that have not developed protective immunity. The aim of the current study was to determine the immunity in a group of vaccinated Sri Lankan military personnel (n = 150; age = 26-44 years) following a complete course of hepatitis B virus surface antigen (HBsAg) vaccination by assessing the antibodies against HBsAg (anti-HBs) levels. Three months after the last dose of the vaccination, blood samples were collected from the study population and tested for anti-HBs levels using a commercially available ELISA. Of the 150 military service men tested, 139 (92.67%) had anti-HBs levels higher than 10 mIU/mL, WHO approved levels for protective immunity against HBV infection. Of the 139 that had sufficient anti-HBs levels, 24% (36/150) had anti-HBs levels between 10 and 100 mIU/mL and 68.67% (103/150) had anti-HBs levels > 100 mIU/mL. Overall, 7.33% (11/150) participants had anti-HBs levels < 10 mIU/mL. Sero-conversion to > 10 mIU/mL anti-HBs was more than 90% in those that were less than 40 years of age and it was less than 90% in those that were more than 40 years of age.

Indexed as

HBsAg immunizationHepatitis B virusProtective immunitySri Lanka

Identifiers

PMID31803814
PMCPMC6863986
OpenAlexW2984303091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.