Evidence map›Paper›PMID 31803771›Full record

ArticleERJ open research2019

Snus in pregnancy and infant birth size: a mother-child birth cohort study.

Ina Kreyberg, Katarina Hilde, Karen Eline S Bains, Kai-Håkon Carlsen, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Christine M Jonassen, Live S Nordhagen, Björn Nordlund and 7 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Ina KreybergFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Katarina HildeFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Karen Eline S BainsFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Kai-Håkon CarlsenFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Berit GranumDept of Toxicology and Risk Assessment, Norwegian Institute of Public Health, Oslo, Norway.
Guttorm HaugenFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Gunilla HedlinAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Christine M JonassenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Live S NordhagenFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-5945-1082
Björn NordlundAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9888-1659
Corina S RueeggOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital and University of Oslo, Oslo, Norway.
Katrine D SjøborgDept of Obstetrics and Gynaecology, Østfold Hospital Trust, Kalnes, Norway.
Håvard O SkjervenFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Anne C StaffFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-9247-5721
Riyas VettukattilFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0002-2152-4933
Karin C Lødrup CarlsenFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
PreventADALL Study Group
Oslo University Hospital · NOKarolinska University Hospital · SEØstfold Hospital Trust · NOH.B. Fuller (United States) · USNorwegian Institute of Public Health · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleWhile recent studies show that maternal use of snus during pregnancy is increasing, the potential effects on infant birth size is less investigated, with conflicting results.

objectivesWe aimed to determine if maternal use of snus during pregnancy influences the infant anthropometric and proportional size measures at birth.

methodsIn 2313 mother-child pairs from the population-based, mother-child birth cohort PreventADALL (Preventing Atopic Dermatitis and ALLergies) in Norway and Sweden, we assessed nicotine exposure by electronic questionnaire(s) at 18 and 34 weeks of pregnancy, and anthropometric measurements at birth. Associations between snus exposure and birth size outcomes were analysed by general linear regression.

resultsBirthweight was not significantly different in infants exposed to snus in general, and up to 18 weeks of pregnancy in particular, when adjusting for relevant confounders including maternal age, gestational age at birth, pre-pregnancy body mass index, parity, fetal sex and maternal gestational weight gain up to 18 weeks. We found no significant effect of snus use on the other anthropometric or proportional size measures in multivariable linear regression models. Most women stopped snus use in early pregnancy.

conclusionExposure to snus use in early pregnancy, with most women stopping when knowing about their pregnancy, was not associated with birth size. We were unable to conclude on effects of continued snus use during pregnancy because of lack of exposure in our cohort.

Identifiers

PMID31803771
PMCPMC6885591
OpenAlexW2989564219

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.