Evidence map›Paper›PMID 31803694›Full record

ArticleFrontiers in pediatrics2019

Zinc Supplementation Promotes a Th1 Response and Improves Clinical Symptoms in Fewer Hours in Children With Pneumonia Younger Than 5 Years Old. A Randomized Controlled Clinical Trial.

Jorge Alberto Acevedo-Murillo, Miguel Leonardo García León, Verónica Firo-Reyes, Jorge Luis Santiago-Cordova, Alejandra Pamela Gonzalez-Rodriguez, Rosa María Wong-Chew

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04983017 (Randomized, Double-Blinded, Placebo-Controlled Study With Immunotype Specific Dietary Supplements to Improve Inflammatory Age® by Edifice Health), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04983017 naterminatednot on this mapstarted 2021, after this paper: background citation

Randomized, Double-Blinded, Placebo-Controlled Study With Immunotype Specific Dietary Supplements to Improve Inflammatory Age® by Edifice Health

TypeinterventionalSponsorEdifice HealthRan2021 to 2022Enrolled781ConditionsChronic Inflammation, InflammagingArmsDietary supplement, Placebo
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  7. Effect of zinc supplementation on symptom reduction and length of hospital stay among pediatric patients with Coronavirus disease 2019 (COVID-19).Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  8. Review
  9. Article
  10. Article
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  12. A literature review on beneficial role of vitamins and trace elements: Evidence from published clinical studies.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2021
    Review
  13. Article
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  15. Article
  16. Herbal immune-boosters: Substantial warriors of pandemic Covid-19 battle.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jorge Alberto Acevedo-MurilloHospital Pediátrico de Coyoacán, Mexico City, Mexico.
Miguel Leonardo García LeónLaboratorio de Investigación en Enfermedades Infecciosas, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Verónica Firo-ReyesServicio de Pediatría, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Jorge Luis Santiago-CordovaLaboratorio de Investigación en Enfermedades Infecciosas, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Alejandra Pamela Gonzalez-RodriguezLaboratorio de Investigación en Enfermedades Infecciosas, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Rosa María Wong-ChewLaboratorio de Investigación en Enfermedades Infecciosas, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Universidad Nacional Autónoma de México · MXHospital General de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

childrenimmune responsepneumoniaTh1 cytokineszinc supplementation

Identifiers

PMID31803694
PMCPMC6874056
OpenAlexW2985305098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.