Evidence map›Paper›PMID 31803304›Full record

ArticleJournal of medicine and life

Rating the environmental and genetic risk factors for colorectal cancer.

M Toma, L Beluşică, M Stavarachi, P Apostol, S Spandole, I Radu, D Cimponeriu

Registry-linked trialAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07529301 (The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07529301 recruitingnot on this map

The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer

Typeobservational_patient_registrySponsorMüşerref Ebru YALÇINRan2026 to 2027Enrolled42ConditionsColorectal Cancer, Functional Status, Respiratory Parameters, Clinical OutcomesArmsPreoperative Assessments, Postoperative Assessments (Daily from Postoperative Day 1 Until Discharge)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M TomaDepartment of Genetics, University of Bucharest, Bucharest, Romania.
L Beluşică"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
M StavarachiDepartment of Genetics, University of Bucharest, Bucharest, Romania.
P ApostolDepartment of Genetics, University of Bucharest, Bucharest, Romania.
S SpandoleDepartment of Genetics, University of Bucharest, Bucharest, Romania.
I RaduDepartment of Genetics, University of Bucharest, Bucharest, Romania.
D CimponeriuDepartment of Genetics, University of Bucharest, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a disease preventable in up to 50% of the patients by lifestyle modifications. The preventive strategy for the decrease in the incidence and mortality of CRC is based on understanding the relations between the environmental and genetic factors. The most important identified risk factors for CRC are aging, personal and familial history of CRC or adenomas, hereditary colon cancer syndromes, dietary patterns, and inflammatory bowel disease. The purpose of this review is to update data referring to environmental and genetic documented factors and CRC risk. Using data from the Medline database, we analyzed reports on CRC risk published between 2000 and 2010. We realized a classification taking into consideration the relative risk (RR) reported for each analyzed factor (RR ranged between 1 and 6.87). The highest RR were represented by the patients with distal advanced cancer (RR = 6.7) and those with high dysplasia adenomas (RR = 6.87). In the future, evaluation and optimisation of screening options will stay at the base of new prevention strategies that will be implemented based on the influence of risk factors identified in each population.

Indexed as

colorectal cancerenvironmental and genetic factorsrelative risk

Identifiers

PMID31803304
PMCPMC6880217

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.