Evidence map›Paper›PMID 31803201›Full record

ArticleFrontiers in plant science2019

Systematic Y2H Screening Reveals Extensive Effector-Complex Formation.

André Alcântara, Jason Bosch, Fahimeh Nazari, Gesa Hoffmann, Michelle Gallei, Simon Uhse, Martin A Darino, Toluwase Olukayode, Daniel Reumann, Laura Baggaley and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Frontiers in microbiology · 2023
    Article
  7. Article
  8. TheJournal of fungi (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 6 countries.

André AlcântaraGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Jason BoschGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Fahimeh NazariGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Gesa HoffmannGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Michelle GalleiGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Simon UhseGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Martin A DarinoGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Toluwase OlukayodeGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Daniel ReumannGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Laura BaggaleyGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Armin DjameiGregor Mendel Institute of Molecular Plant Biology, Vienna, Austria.
Gregor Mendel Institute of Molecular Plant Biology · ATInstitute of Science and Technology Austria · ATIranian Research Institute of Plant Protection · IRLeibniz Institute of Plant Genetics and Crop Plant Research · DEUniversity of Saskatchewan · CA

Funding

Austrian Science Fund FWF I 3033Austrian Science Fund FWF P 27818
6 · The paper itself

Abstract

During infection pathogens secrete small molecules, termed effectors, to manipulate and control the interaction with their specific hosts. Both the pathogen and the plant are under high selective pressure to rapidly adapt and co-evolve in what is usually referred to as molecular arms race. Components of the host's immune system form a network that processes information about molecules with a foreign origin and damage-associated signals, integrating them with developmental and abiotic cues to adapt the plant's responses. Both in the case of nucleotide-binding leucine-rich repeat receptors and leucine-rich repeat receptor kinases interaction networks have been extensively characterized. However, little is known on whether pathogenic effectors form complexes to overcome plant immunity and promote disease.

Indexed as

effector proteinsplant pathogenprotein–protein interaction networkUstilago maydisyeast-two-hybrid

Identifiers

PMID31803201
PMCPMC6872519
OpenAlexW2981753953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.