Evidence map›Paper›PMID 31803184›Full record

ArticleFrontiers in immunology2019

Mannan Enhances IL-12 Production by Increasing Bacterial Uptake and Endosomal Degradation in

Ronja Mathiesen, Helene M S Eld, Juliane Sørensen, Eva Fuglsang, Lisbeth Drozd Lund, Valentina Taverniti, Hanne Frøkiær

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Ronja MathiesenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Helene M S EldDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Juliane SørensenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Eva FuglsangDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Lisbeth Drozd LundDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Valentina TavernitiDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Hanne FrøkiærDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mannose receptor (MR) is a C-type lectin involved in endocytosis and with a poorly defined ability to modulate cellular activation. We investigated the effect of mannan treatment prior to stimulation of murine bone marrow-derived dendritic cells with the Gram-positive bacteria

Indexed as

EndocytosisAnimalsChlorpromazineDendritic CellsEndosomesInterleukin-12Lactobacillus acidophilusLectins, C-TypeMannansMannose-Binding LectinsMannose ReceptorMiceMice, Inbred C57BLReceptors, Cell SurfaceSignaling Lymphocytic Activation Molecule Family Member 1Staphylococcus aureusChlorpromazineInterleukin-12Lectins, C-TypeMannansMannose-Binding LectinsMannose ReceptorReceptors, Cell SurfaceSignaling Lymphocytic Activation Molecule Family Member 1Slamf1 protein, mousedendritic cellsendosomal killingGram-positive bacteriaIL-12mannose receptorphagocytosisSLAMF1

Identifiers

PMID31803184
PMCPMC6873232
OpenAlexW2986850803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.