Evidence map›Paper›PMID 31802860›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2019

Nebulized Colistin And Continuous Cyclic Azithromycin In Severe COPD Patients With Chronic Bronchial Infection Due To

Concepción Montón, Elena Prina, Xavier Pomares, Jose R Cugat, Antonio Casabella, Joan Carles Oliva, Miguel Gallego, Eduard Monsó

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Concepción MontónDepartment of Respiratory Medicine, Hospital De Sabadell, Institut Universitari Parc Taulí-UAB, Sabadell, Spain.
Elena PrinaDepartment of Respiratory Medicine, Hospital De Sabadell, Institut Universitari Parc Taulí-UAB, Sabadell, Spain.
Xavier PomaresDepartment of Respiratory Medicine, Hospital De Sabadell, Institut Universitari Parc Taulí-UAB, Sabadell, Spain.ORCID 0000-0002-2783-414X
Jose R CugatDepartment of Respiratory Medicine, Fundació Althaia, Manresa, Spain.ORCID 0000-0002-9551-3794
Antonio CasabellaLaboratory of Microbiology-UDIAT, Institut Universitari Parc Taulí-UAB, Sabadell, Spain.
Joan Carles OlivaEpidemiology and Assessment Unit, Fundació Parc Taulí, Universitat Autònoma de Barcelona, Sabadell, Spain.
Miguel GallegoDepartment of Respiratory Medicine, Hospital De Sabadell, Institut Universitari Parc Taulí-UAB, Sabadell, Spain.ORCID 0000-0002-8882-4033
Eduard MonsóDepartment of Respiratory Medicine, Hospital De Sabadell, Institut Universitari Parc Taulí-UAB, Sabadell, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESDeleted InstitutionAlthaia · ESCorporació Sanitària Parc Taulí · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Long-term use of nebulized or oral antibiotics is common in the treatment of cystic fibrosis and non-cystic fibrosis bronchiectasis. To date, however, few studies have focused on the use of nebulized antibiotics in COPD patients. The aims of this study are: to establish whether a combination of nebulized colistin plus continuous cyclic azithromycin in severe COPD patients with chronic bronchial infection due to Material and methods: A retrospective cohort was created for the analysis of patients with severe COPD and chronic bronchial infection due to Results: We analyzed 32 severe COPD patients who received nebulized colistin for at least three months (median 17 months [IQR 7-24]). All patients but one received combination therapy with continuous cyclic azithromycin (median 24 months [IQR 11-30]). A significant reduction in the number of ECOPD from baseline of 38.3% at two years of follow-up was observed, with a clear decrease in Conclusion: In patients with severe COPD and chronic bronchial infection due to

Indexed as

Administration, InhalationAgedAged, 80 and overAnti-Bacterial AgentsAzithromycinBronchiColistinDisease ProgressionDrug Therapy, CombinationFemaleHumansMaleNebulizers and VaporizersPseudomonas InfectionsPulmonary Disease, Chronic ObstructiveRespiratory Tract InfectionsAnti-Bacterial AgentsAzithromycinColistinazithromycincolistinCOPDexacerbationPseudomonas aeruginosa

Identifiers

PMID31802860
PMCPMC6802559
OpenAlexW2981267625

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.