Evidence map›Paper›PMID 31802761›Full record

ReviewPathobiology : journal of immunopathology, molecular and cellular biology2020

The Spectrum of Aggressive Mastocytosis: A Workshop Report and Literature Review.

Roos Leguit, Konnie Hebeda, Marcus Kremer, Jon van der Walt, Umberto Gianelli, Alexandar Tzankov, Attilio Orazi

Open access · hybridAbstract readReview
In one paragraph

Review in Pathobiology : journal of immunopathology, molecular and cellular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Precision Medicine in Systemic Mastocytosis.Medicina (Kaunas, Lithuania) · 2021
    Review
  14. Mastocytosis and Mast Cell Activation Disorders: Clearing the Air.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 6 countries.

Roos LeguitDepartment of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands, R.J.Leguit-2@umcutrecht.nl.
Konnie HebedaDepartment of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
Marcus KremerPathology, Städtisches Klinikum München, Munich, Germany.
Jon van der WaltDepartment of Histopathology, Guy's and St. Thomas' Hospital, London, United Kingdom.
Umberto GianelliPathology Unit, Department of Pathophysiology and Transplantation, University of Milan and IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Alexandar TzankovInstitute of Pathology, University of Basel, Hospital, Basel, Switzerland.
Attilio OraziDepartment of Pathology, Texas Tech University Health Sciences Center El Paso, El Paso, Texas, USA.
München Klinik · DERadboud University Nijmegen · NLSt Thomas' Hospital · GBTexas Tech University · USUniversity of Basel · CHUniversity of Milan · ITUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most cases of mastocytosis are indolent, usually cutaneous mastocytosis or indolent systemic mastocytosis (SM). Aggressive mast cell (MC) diseases are very rare and often fatal. They can develop de novo or due to progression of indolent forms and can present in different ways; either as MC sarcoma or as advanced SM which includes aggressive SM, MC leukemia, and SM with an associated hematological neoplasm. This review will describe these different aggressive forms of mastocytosis, illustrated by cases submitted to the workshop of the 18th Meeting of the European Association for Haematopathology, Basel 2016, organized by the European Bone Marrow Working Group. In addition, the diagnostic criteria for identifying myelomastocytic leukemia, an aggressive myeloid neoplasm with partial MC differentiation that falls short of the criteria for SM, and disease progression in patients with established mastocytosis are discussed.

Indexed as

Bone MarrowCongresses as TopicDiagnosis, DifferentialDisease ProgressionEuropeHumansLeukemia, Mast-CellMastocytosisMastocytosis, SystemicMyeloproliferative DisordersAggressive mastocytosisBone marrow biopsyEuropean Association for Haematopathology workshopMast cell leukemiaMast cell sarcomaMastocytosis

Identifiers

PMID31802761
PMCPMC7158230
OpenAlexW2993969686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.