ArticleThe American journal of tropical medicine and hygiene2020
Development of a Chitosan-Vaseline Gauze Dressing with Wound-Healing Properties in Murine Models.
Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Design of a Gelatin/Carboxymethyl Cellulose Hydrogel Containing Myrtus Communis Extract with Anti-inflammatory Capabilities for Accelerated Wound Healing; in Vitro and in Vivo Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Article
- Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract ofInternational journal of molecular sciences · 2026Article
- Comparative Evaluation of Single and Combination Pharmacologic and Device-Based Anti-scar Therapies in a Murine Linear Wound Model.Aesthetic plastic surgery · 2026Article
- Clinical observation of Wound Care Ointment on split-thickness skin graft donor site healing.International journal of burns and trauma · 2026Article
- Electrospinning strategies targeting fibroblast for wound healing of diabetic foot ulcers.APL bioengineering · 2025Review
- Spiroconjugated 1,2,3-triazolo[5,1-Research in pharmaceutical sciences · 2024Article
- Current status and progress in research on dressing management for diabetic foot ulcer.Frontiers in endocrinology · 2023Review
- The Fabrication of Docetaxel-Containing Emulsion for Drug Release Kinetics and Lipid Peroxidation.Pharmaceutics · 2022Article
- Effects of Natural Brown Cotton Bleached Gauze on Wound Healing.Materials (Basel, Switzerland) · 2022Article
- Efficiency of Multifunctional Antibacterial Hydrogels for Chronic Wound Healing in Diabetes: A Comprehensive Review.International journal of nanomedicine · 2022Review
- Flexible electrical stimulation device with Chitosan-Vaseline® dressing accelerates wound healing in diabetes.Bioactive materials · 2021Article
- Application and nursing key points of wet dressings on the intestinal stoma after enterostomy.American journal of translational research · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound dressings are always needed after skin injury; however, most of the dressings still leave room for improvement. Here, we would like to develop an effective dressing with the ability to improve wound healing. A chitosan-Vaseline gauze (CVG) dressing was developed by coating the chitosan mixture and Vaseline on sterile gauze with subsequent drying. Infrared spectroscopy and electron microscopy were used to investigate the miscibility and structure of the dressing. The cytotoxicity and antibacterial nature were evaluated in vitro. The studies of water retention rate, wound healing, and tissue compatibility were carried out over a period of 14 days on full-thickness skin wounds of male Sprague-Dawley rats. It was observed that the CVG dressing demonstrated functional structure by miscibility, non-cytotoxicity, and good antibacterial effects against both Gram-positive and Gram-negative bacteria. The water retention rate incresased up to 25% after applying CVG for 3 hours. Besides, CVG treatment increased angiogenesis and improved microvascular density in wounds. The wounds treated with CVG showed size deduction with new collagen aggregations similar to those in the normal dermis. All the aforementioned results suggest that CVG dressing could be a promising candidate for wound treatment.
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