ArticleJournal of chemical ecology2019
Toxicity and Alkaloid Profiling of the Skin of the Golfo Dulcean Poison Frog Phyllobates vittatus (Dendrobatidae).
Article in Journal of chemical ecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Meta-analysis of tadpole taste tests: consumption of anuran prey across development and predator strategies.Oecologia · 2022Pooled it
- Lack of tetrodotoxin analogues and individual metabolomic profiling of the cryptic frog Colostethus imbricolus.PloS one · 2026Article
- Nuance in the Narrative of a Brown Poison Frog: Environmental Alkaloids and Specialized Foraging in a Presumed Toxin-Free and Diet-Generalized Species.Journal of chemical ecology · 2025Article
- A draft genome assembly for the dart-poison frogGigaByte (Hong Kong, China) · 2025Article
- Eco-Metabolomics Applied to the Chemical Ecology of Poison Frogs (Dendrobatoidea).Journal of chemical ecology · 2023Review
- Linking Predator Responses to Alkaloid Variability in Poison Frogs.Journal of chemical ecology · 2023Article
- How do batrachotoxin-bearing frogs and birds avoid self intoxication?The Journal of general physiology · 2021Article
- First characterization of toxic alkaloids and volatile organic compounds (VOCs) in the cryptic dendrobatid Silverstoneia punctiventris.Frontiers in zoology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
Frogs in the genus Phyllobates are known for the presence of batrachotoxin, a highly toxic alkaloid, in their skin. Nevertheless, Phyllobates frogs from Costa Rica and Panama (P. lugubris and P. vittatus) are considered non-toxic, as they have been reported to harbor low concentrations of this alkaloid. However, the potential toxicity of Central American Phyllobates has not been assessed experimentally. Our goal was to determine the toxicity of the whole skin of P. vittatus, an endemic species from the Southeastern Pacific region of Costa Rica. We performed median lethal dose (LD
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.