Evidence map›Paper›PMID 31802377›Full record

ReviewHeart failure reviews2020

Acutely decompensated versus acute heart failure: two different entities.

Andrew Xanthopoulos, Javed Butler, John Parissis, Eftihia Polyzogopoulou, John Skoularigis, Filippos Triposkiadis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. The predictive value of the triglyceride-glucose index for five-year all-cause mortality differs between patients with acutePostepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025
    Article
  2. Cardiology research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Andrew XanthopoulosDepartment of Cardiology, Larissa University General Hospital, P.O. Box 1425, 411 10, Larissa, Greece.
Javed ButlerDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
John ParissisHeart Failure Unit, Second Cardiology Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Eftihia PolyzogopoulouEmergency Medicine Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
John SkoularigisDepartment of Cardiology, Larissa University General Hospital, P.O. Box 1425, 411 10, Larissa, Greece.
Filippos TriposkiadisDepartment of Cardiology, Larissa University General Hospital, P.O. Box 1425, 411 10, Larissa, Greece. ftriposkiadis@gmail.com.ORCID 0000-0001-6433-4016
University Hospital of Larissa · GRNational and Kapodistrian University of Athens · GRJackson Memorial Hospital · US

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI COMPRETTA, CAROLINE E. · 2016 to 2025
$38.2M
NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

Heart failure (HF) has been classified in chronic HF (CHF) and acute HF (AHF). The latter has been subdivided in acutely decompensated chronic HF (ADCHF) defined as the deterioration of preexisting CHF and de novo AHF defined as the rapid development of new symptoms and signs of HF that requires urgent medical attention. However, ADCHF and de novo AHF have fundamental pathophysiological differences. Most importantly, the typical illness trajectory of HF, which is similar to that of other chronic organ diseases including lung, renal, and liver failure, features a gradual decline, with acute episodes usually related to disease evolution followed by partial recovery. Thus, ADCHF should be considered part of the natural history of CHF and renamed CHF exacerbation (CHFE) in accordance with the appropriate terminology used in chronic obstructive pulmonary disease. AHF, in turn, should include only acute de novo HF. The clinical implications of this paradigm shift will be in CHFE the change in focus from in-hospital to optimal ambulatory CHF management aiming at primary and secondary CHFE prevention, while in AHF, the institution of measures for in-hospital limitation of cardiac injury and prevention or retardation of symptomatic CHF development.

Indexed as

Disease ManagementRegistriesAcute DiseaseHeart FailureHumansAcutely decompensated chronic HFChronicClassificationExacerbation

Identifiers

PMID31802377
OpenAlexW2994185822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.