Evidence map›Paper›PMID 31802245›Full record

ArticleMikrochimica acta2019

Multiplexed fluorometric determination for three microRNAs in acute myocardial infarction by using duplex-specific nuclease and MoS

Xue Zhu, Ke Wang, Yan Jin, Shuya Wang, Xiaoxiao Liu, Haohao Liu, Peiling Zhou, Chengjian Yang, Zhijun Han

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xue ZhuKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, Jiangsu Province, People's Republic of China.
Ke WangKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, Jiangsu Province, People's Republic of China.
Yan JinDepartment of Cardiology, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China.
Shuya WangDepartment of Cardiology, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China.
Xiaoxiao LiuDepartment of Cardiology, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China.
Haohao LiuDepartment of Laboratory Medicine, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China.
Peiling ZhouDepartment of Cardiology, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China.
Chengjian YangDepartment of Cardiology, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China. doctory2071@sina.com.
Zhijun HanDepartment of Laboratory Medicine, The Affiliated Wuxi NO.2 People's Hospital of Nanjing Medical University, Wuxi, 214002, Jiangsu Province, People's Republic of China. zjhan1125@163.com.
Nanjing Medical University · CNWuxi No.2 People's Hospital · CN

Funding

Jiangsu Young Medical Talents QNRC2016167Natural Science Foundation of Jiangsu Province BK20171147Six Talent Peaks Project in Jiangsu Province WSW-047The Major Science and Technology Projects of Wuxi City MS201653The Major Science and Technology Projects of Wuxi City Z201804The Science and Technology Projects of Wuxi City WX18IVJN016
6 · The paper itself

Abstract

Circulating microRNAs are of diagnostic value for acute myocardial infarction (AMI). This study describes a fluorometric assay for multiplexed detection of the AMI biomarkers microRNA-499, microRNA-133a and microRNA-1. The assay involves the following two steps: (a) duplex-specific nuclease (DSN)-mediated signal amplification using aptamer-based sensor; (b) MoS

Indexed as

Acute DiseaseCase-Control StudiesDeoxyribonucleasesDisulfidesFemaleFluorometryHumansMaleMicroRNAsMiddle AgedMolybdenumMyocardial InfarctionNanostructuresDeoxyribonucleasesDisulfidesMicroRNAsMolybdenummolybdenum disulfideAcute myocardial infarctionDuplex-specific nuclease-mediated signal amplificationMicroRNA-1MicroRNA-133aMicroRNA-499MoS2 nanosheets-based fluorometric signal detectionQuantitative real time-PCR

Identifiers

PMID31802245
OpenAlexW2993460607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.