Evidence map›Paper›PMID 31802218›Full record

ArticleJournal of neurology2020

Suicidal risk and demoralization in Parkinson disease.

Mohamed Elfil, Nada Ahmed, Amritha Alapati, Rucha Bahekar, Mohamed Kandil, Christine Kim, Sara Schaefer, Sule Tinaz, Amar S Patel, John M de Figueiredo and 2 more

Abstract read
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In one paragraph

Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Suicide in neurodegenerative diseases: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  12. A cross-sectional study on demoralization in prostate cancer patients: the role of masculine self-esteem, depression, and resilience.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mohamed ElfilDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Nada AhmedDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Amritha AlapatiDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Rucha BahekarDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Mohamed KandilDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Christine KimDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Sara SchaeferDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Sule TinazDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Amar S PatelDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
John M de FigueiredoDepartment of Psychiatry, Yale, New Haven, CT, USA.
Elan D LouisDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA.
Brian B KooDepartment of Neurology, Yale University, 15 York Street, LCI 710, New Haven, CT, 06510, USA. brian.koo@yale.edu.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to determine suicide risk and lifetime suicidal ideation in Parkinson disease (PD) patients versus controls and how depression, demoralization, and insomnia are associated with suicidality.

methodsIn this case-control study, PD patients and matched controls were recruited from movement disorder clinics, Michael J. Fox Foundation, and Research Match websites. Suicide risk and suicidal ideation were assessed using the Suicidal Behavior Questionnaire-revised (SBQ-R) and Columbia-Suicide Severity Rating Scale. Lifetime depression was assessed using the Brief Lifetime Depression Scale, sleep using Insomnia Severity Index (ISI), demoralization using Diagnostic Criteria for Psychosomatic Research and Kissane Demoralization Scales, and non-motor symptoms using UPDRS Non-Motor Aspects of Experiences of Daily Living scale (nM-EDL).

results186 PD participants and 177 controls were matched for age (64.2 ± 7.7 years), sex (48.8% female), and socioeconomics. PD participants were not more likely than controls to have high suicide risk (SBQ-R ≥ 7) (7.5% vs. 11.3%; p = 0.22) or to have had a lifetime suicide plan or attempt (2.7% vs. 5.1%; p = 0.24), but were less likely to have had lifetime suicidal ideation (23.1% vs. 35.0%; p = 0.01). PD participants were more likely than controls to have lifetime depression history (34.4% vs. 20.9%; p = 0.004), and demoralization (19.9% vs. 10.7%; p = 0.02), and had higher ISI scores (8.7 ± 5.8 vs. 5.1 ± 4.5; p < 0.0001). PD patients with high versus normal suicide risk had higher nM-EDL scores (16.5 ± 6.8 vs. 10.7 ± 5.9; p = 0.002), and more demoralization (71.4% vs. 21.5%; p < 0.0001).

conclusionsSuicide risk is not elevated and suicidal ideation is uncommon in PD, despite the high prevalence of depression and demoralization.

Indexed as

DemoralizationAgedCase-Control StudiesDepressionFemaleHumansMaleMiddle AgedParkinson DiseasePrevalenceSleep Initiation and Maintenance DisordersSuicidal IdeationSuicideUnited StatesDemoralizationDepressionParkinson diseasePDSuicidal ideationSuicide

Identifiers

PMID31802218
OpenAlexW2994344464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.