ArticleSkeletal radiology2020
Dual-energy CT in the differentiation of crystal depositions of the wrist: does it have added value?
Article in Skeletal radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Spatiotemporal immune gradients in gout: immune response-driven activation of the NLRP3-IL-1β axis and its transition to trained immunity.Frontiers in immunology · 2026Review
- Application of computed tomography angiography imaging in coronary heart disease screening and analysis of associated risk factors.Quantitative imaging in medicine and surgery · 2024Article
- Material decomposition approaches for monosodium urate (MSU) quantification in gouty arthritis: a (bio)phantom study.European radiology experimental · 2024Article
- Assessment of thoracic disc degeneration using dual-energy CT-based collagen maps.European radiology experimental · 2024Article
- Virtual noncontrast images reveal gouty tophi in contrast-enhanced dual-energy CT: a phantom study.European radiology experimental · 2024Article
- Computed tomography-current status and future directions for arthritis imaging.Therapeutic advances in musculoskeletal disease · 2024Review
- Influence of contrast medium on tophus detection using dual-energy CT: phantom study and clinical illustration.European radiology experimental · 2023Article
- Four-dimensional computed tomography detects dynamic three-dimensional pathologies of the wrist in patients with calcium pyrophosphate deposition disease.Frontiers in medicine · 2023Article
- [Detection of Monosodium Urate Crystal of Hand and Wrist in Suspected Gouty Arthritis Patients on Dual-Energy CT and Relationship with Serum Urate Level].Journal of the Korean Society of Radiology · 2023Article
- Article
- Future of Low-Dose Computed Tomography and Dual-Energy Computed Tomography in Axial Spondyloarthritis.Current rheumatology reports · 2022Review
- [Clinical classification and treatment experience of wrist gouty arthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021Article
- Dual-energy CT collagen density mapping of wrist ligaments reveals tissue remodeling in CPPD patients: first results from a clinical cohort.Skeletal radiology · 2021Article
- Imaging of Joints and Bones in Autoinflammation.Journal of clinical medicine · 2020Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the ability of dual-energy computed tomography (DECT) to improve diagnostic discrimination between gout and other crystal arthropathies such as calcium pyrophosphate deposition disease (CPPD) of the wrist in a clinical patient population. MATERIALS AND
methodsThis retrospective case-control study included 29 patients with either gout (case group; n = 9) or CPPD (control group; n = 20) who underwent DECT of the wrist for clinically suspected crystal arthropathy. Color-coded urate and enhanced calcium as well as virtual 120 kVe blended images were reconstructed from the DECT datasets. Two independent and blinded readers evaluated each reconstructed dataset for the presence of depositions in 17 predefined regions. Additionally, a global diagnosis was made first for 120 kVe images only, based solely on morphologic criteria, and subsequently for all reconstructed images.
resultsSensitivity for the global diagnosis of gout was 1.0 (95% CI 0.63-1) for both DECT and 120 kVe images with specificities of 0.70 (95% CI 0.46-0.87) for DECT and 0.80 (95% CI 0.56-0.93) for 120 kVe images. Color-coded DECT images did not detect more depositions than monochrome standard CT images.
conclusionDiscrimination of crystal arthropathies of the wrist is limited using DECT and primarily relying on color-coded images. Evaluation of morphologic criteria on standard CT images is essential for accurate diagnosis.
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