Evidence map›Paper›PMID 31801600›Full record

ArticleTrials2019

Fire acupuncture for mild to moderate knee osteoarthritis: a protocol for a randomized controlled pilot trial.

Yuan-Bo Fu, Bin Li, San-Feng Sun, Hui-Lin Liu, Xin Wang, Shao-Song Wang, Fan Zhang, Xin Du, Du-Juan Ge, Lei Shang and 5 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Yuan-Bo FuThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Bin LiThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
San-Feng SunBeijing Huairou District Hospital of Traditional Chinese Medicine, No. 1 Houheng Street, Huairou District, Beijing, 101400, China.
Hui-Lin LiuThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Xin WangThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Shao-Song WangThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Fan ZhangThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Xin DuThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Du-Juan GeBeijing Huairou District Hospital of Traditional Chinese Medicine, No. 1 Houheng Street, Huairou District, Beijing, 101400, China.
Lei ShangBeijing Huairou District Hospital of Traditional Chinese Medicine, No. 1 Houheng Street, Huairou District, Beijing, 101400, China.
Rui-Li LiangBeijing Huairou District Hospital of Traditional Chinese Medicine, No. 1 Houheng Street, Huairou District, Beijing, 101400, China.
Li-Na WangBeijing Huairou District Hospital of Traditional Chinese Medicine, No. 1 Houheng Street, Huairou District, Beijing, 101400, China.
Fang YuanThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China.
Jing-Qing SunThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China. sjqdoctor@163.com.
Jun-Wei ChenThe Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguanhou Street, Dongcheng District, Beijing, 100010, China. 847431304@qq.com.ORCID http://orcid.org/0000-0001-7364-1288
Capital Medical University · CNBeijing University of Chinese Medicine · CN

Funding

Beijing Huairou District Science and Technology Plan Project,Beijing Key Laboratory of Acupuncture Neuromodulation,Beijing,China NY2019-6Beijing Municipal Hospital Research and Development Program PZ2019019
6 · The paper itself

Abstract

backgroundKnee osteoarthritis (KOA) is one of the most common bone and joint diseases. As one of the main non-drug therapies, acupuncture is widely used to treat KOA, although the evidence for its efficacy is inconclusive. The objective of this pilot trial is to clarify the clinical efficacy and safety of fire acupuncture in the treatment of mild to moderate KOA and to provide high-quality data for further research. METHODS/

designThis study is a prospective randomized controlled pilot trial in which 120 patients with mild to moderate KOA will be randomly allocated in equal proportions to a fire acupuncture group or a general acupuncture group. They will receive acupuncture for six sessions over 2 weeks. The primary end point is success rate, which will be calculated based on the change from baseline of the pain and function scores in the Western Ontario and McMaster Universities Osteoarthritis Index at 4 weeks. Secondary end points include the proportion of patients achieving clinical improvement based on: (1) the OMERACT-OARSI responder criteria, (2) levels of matrix metalloproteinase 3, interleukin 1β, and tumor necrosis factor α in blood, and (3) a subjective efficacy evaluation from patients.

trial registrationChinese Clinical Trial Registry, ChiCTR1800019162. Registered on 29 October 2018.

Indexed as

Acupuncture TherapyOsteoarthritis, KneeAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedMulticenter Studies as TopicPilot ProjectsProspective StudiesRandomized Controlled Trials as TopicResearch DesignBasic health managementFire AcupunctureKnee Osteoarthritis

Identifiers

PMID31801600
PMCPMC6894354
OpenAlexW2992291896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.