Evidence map›Paper›PMID 31801593›Full record

ArticleTrials2019

Fire needle acupuncture or moxibustion for chronic plaque psoriasis: study protocol for a randomized controlled trial.

Zhaoxia Chen, Dongmei Zhou, Yan Wang, Haibing Lan, Xingwu Duan, Bohua Li, Jingxia Zhao, Wei Li, Zhengrong Liu, Tingting Di and 5 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Zhaoxia ChenBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Dongmei ZhouBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Yan WangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Haibing LanGulou Hospital of Traditional Chinese Medicine of Beijing, Beijing, 100009, China.
Xingwu DuanDongzhimen Hospital of Beijing University of Chinese Medicine, Beijing, 100700, China.
Bohua LiBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Jingxia ZhaoBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Wei LiBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Zhengrong LiuBeijing University of Chinese Medicine, Beijing, 100029, China.
Tingting DiBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Xinwei GuoBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Jinchao ZhangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Bo LiBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Shuo FengBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China. fengshuo_1988@126.com.ORCID http://orcid.org/0000-0002-9155-4652
Ping LiBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China. liping411@126.com.
Capital Medical University · CNBeijing Hospital of Traditional Chinese Medicine · CNBeijing University of Chinese Medicine · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CN

Funding

Beijing Traditional Chinese Medicine Science and Technology Development Fund Project QN2018-21Capital's Funds for Health Improvement and Research CFH2018-2-1162
6 · The paper itself

Abstract

backgroundPsoriasis is a chronic, immune-mediated disorder with chronic plaque psoriasis being the primary manifestation during the remission stage. Patients often have a slow course and long history of the disease. The refractory type of psoriasis is a stubborn rash that does not subside easily. We designed this randomized controlled trial to compare the effectiveness and relapse rates of plaque psoriasis in patients treated with either acupuncture, moxibustion or calcipotriol ointment. The ultimate aim of the study is to select an effective traditional Chinese medicine therapy for patients with plaque psoriasis.

methodsThe study will be a multicenter, prospective, randomized controlled trial that compares the effectiveness of fire needle therapy, moxibustion and calcipotriol ointment. In total, 160 patients with plaque psoriasis who meet the inclusion criteria will be recruited from three hospitals in Beijing and then randomly assigned to receive either fire needle therapy (group A1), moxibustion (group A2) or calcipotriol ointment (group B). All participants will receive an 8-week treatment and will then be followed up for another 24 weeks, with time points at weeks 12 and 24 after treatment completion. The primary outcomes to be measured are relapse rates and psoriasis area and severity index score of the target lesions. In addition, the target lesion onset time, dermatology life quality index, traditional Chinese medicine syndrome score, and the relapse interval of the target lesion will be measured. Adverse events will be recorded for safety assessment. DISCUSSION: The aim of this study is to determine whether fire needle therapy or moxibustion could improve the clinical effectiveness for psoriasis lesions and reduce the relapse rate. Once completed, it will provide information regarding therapeutic evaluation on fire needle therapy or moxibustion for plaque psoriasis, which will assist clinicians in selecting the most effective treatment options for patients.

trial registrationInternational Clinical Trials Registry Platform (ICTRP), ChiCTR1800019588. Registered on 19 November 2018.

Indexed as

Acupuncture TherapyMoxibustionPsoriasisAdolescentAdultAgedCalcitriolChronic DiseaseHumansMiddle AgedMulticenter Studies as TopicOutcome Assessment, Health CareProspective StudiesRandomized Controlled Trials as TopicResearch DesignYoung AdultcalcipotrieneCalcitriolClinical effectivenessFire needle therapyMoxibustionPlaque psoriasisRelapse rate

Identifiers

PMID31801593
PMCPMC6894135
OpenAlexW2993391713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.