Evidence map›Paper›PMID 31801515›Full record

ArticleBMC medical informatics and decision making2019

Natural language processing for populating lung cancer clinical research data.

Liwei Wang, Lei Luo, Yanshan Wang, Jason Wampfler, Ping Yang, Hongfang Liu

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liwei WangDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, 55901, USA.
Lei LuoDepartment of Good Clinical Practice, Guizhou Province People's Hospital, Guiyang, China.
Yanshan WangDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, 55901, USA.
Jason WampflerDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, 55901, USA.
Ping YangDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, 55901, USA.
Hongfang LiuDepartment of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, 55901, USA. liu.hongfang@mayo.edu.

Funding

Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Advancing Cancer Pharmacoepidemiology Research Through EHRs and InformaticsU24CA194215 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAO, CUI, YANG, PING · 2016 to 2020
$3.3M
NCATS NIH HHS U01 TR002062NCI NIH HHS U24 CA194215
6 · The paper itself

Abstract

backgroundLung cancer is the second most common cancer for men and women; the wide adoption of electronic health records (EHRs) offers a potential to accelerate cohort-related epidemiological studies using informatics approaches. Since manual extraction from large volumes of text materials is time consuming and labor intensive, some efforts have emerged to automatically extract information from text for lung cancer patients using natural language processing (NLP), an artificial intelligence technique.

methodsIn this study, using an existing cohort of 2311 lung cancer patients with information about stage, histology, tumor grade, and therapies (chemotherapy, radiotherapy and surgery) manually ascertained, we developed and evaluated an NLP system to extract information on these variables automatically for the same patients from clinical narratives including clinical notes, pathology reports and surgery reports.

resultsEvaluation showed promising results with the recalls for stage, histology, tumor grade, and therapies achieving 89, 98, 78, and 100% respectively and the precisions were 70, 88, 90, and 100% respectively.

conclusionThis study demonstrated the feasibility and accuracy of automatically extracting pre-defined information from clinical narratives for lung cancer research.

Indexed as

Artificial IntelligenceNatural Language ProcessingData CollectionElectronic Health RecordsFemaleHumansLung NeoplasmsNarrationNeoplasm GradingResearchHistologyLung cancerNatural language processingStageTreatmentsTumor grade

Identifiers

PMID31801515
PMCPMC6894100

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.