ArticleBMC complementary and alternative medicine2019
Immunomodulatory and anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum leaves and its effect on lung pathological changes in an ovalbumin-induced rat model of asthma.
Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 97 citations in OpenAlex.
- The Use of Spice Herbs May Reduce Chronic Inflammation and Improve the Quality of Life of Women with Metabolic Syndrome-A Narrative Review.Nutrients · 2026Review
- Unveiling the biological activity of Ocimum basilicum through nano graphene oxide foliar application with chemical and organic fertilizers broadcasting.Scientific reports · 2025Article
- Effect of Light Intensity and Light Spectrum of LED Light Sources on Photosynthesis and Secondary Metabolite Synthesis inPlants (Basel, Switzerland) · 2025Article
- Healing effects of topically applied Ocimum basilicum L. on excisional wounds in mice.Acta cirurgica brasileira · 2025Article
- Review
- Green synthesis of silver nanoparticle prepared with Ocimum species and assessment of anticancer potential.Scientific reports · 2024Article
- Echinochrome exhibits anti-asthmatic activity through the suppression of airway inflammation, oxidative stress, and histopathological alterations in ovalbumin-induced asthma in BALB/c mice.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Antimicrobial and Other Pharmacological Properties ofMolecules (Basel, Switzerland) · 2024Review
- Antiasthmatic Medicinal Plants of Tanzania: An Ethnomedicinal and Ethnopharmacological Review.TheScientificWorldJournal · 2024Review
- An Updated Comprehensive Review of Plants and Herbal Compounds with Antiasthmatic Effect.Evidence-based complementary and alternative medicine : eCAM · 2024Review
- Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice.Iranian journal of basic medical sciences · 2024Article
- Medicinal plants used in Gabon for prophylaxis and treatment against COVID-19-related symptoms: an ethnobotanical survey.Frontiers in pharmacology · 2024Article
- Effects of Dietary Supplement of Basil Extract on Biochemical and Immunological Parameters and Growth Performance inAquaculture nutrition · 2024Article
- Potential antihypertensive activity of novel peptides from green basil leaves.BMC complementary medicine and therapies · 2023Article
- Ethanol extract of basil (Journal of medicine and life · 2023Article
- Assessment of the Oxidative Damage and Genotoxicity of Titanium Dioxide Nanoparticles and Exploring the Protective Role of Holy Basil Oil Nanoemulsions in Rats.Biological trace element research · 2023Article
- Anti-inflammatory, immunomodulatory and anti-oxidant effects ofIranian journal of basic medical sciences · 2023Review
- The effect of combining basil seeds and gum Arabic on the healing process of experimental acetic acid-induced ulcerative colitis in rats.Journal of traditional and complementary medicine · 2022Article
- Review
- Anti-Coronavirus Efficiency and Redox-Modulating Capacity of Polyphenol-Rich Extracts from Traditional Bulgarian Medicinal Plants.Life (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOcimum species (Lamiaceae) has been traditionally used for treatment of upper respiratory tract infections, bronchitis, coughs, sore throat, and wound healing. The Immunomodulatory and anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum (O. basilicum) leaves was examined in ovalbumin sensitized animals.
methodsWistar rats were divided to six groups; non-sensitized, sensitized to ovalbumin, sensitized and treated with dexamethasone (1.25 μg/mL), and O. basilicum extract (0.75, 1.50 and 3.00 mg/mL) in drinking water for 21 days. The levels of interleukin 4 (IL-4), interferon gamma (IFN-γ), IFN-γ/IL-4 ratio, immunoglobulin E (IgE), phospholipase A
resultsA significant increase in IL-4, IgE, PLA
conclusionThe improvement effects of O. basilicum on pathological changes, immunological and inflammatory markers in sensitized rats comparable or even more potent than dexamethasone suggests the therapeutic potential of the plant in asthma.
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