Evidence map›Paper›PMID 31801489›Full record

ArticleBMC pediatrics2019

Differences in attitudes to feeding post repair of Gastroschisis and development of a standardized feeding protocol.

Donna Hobson, Kaye Spence, Amit Trivedi, Gordon Thomas

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06878950 (The GAIN Study), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06878950 narecruitingnot on this mapstarted 2025, after this paper: background citation

The GAIN Study: The Gastroschisis And Early Infant Nutrition Study

TypeinterventionalSponsorUniversity of California, DavisRan2025 to 2029Enrolled20ConditionsGastroschisisArmsEarly Feeding Protocol
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  6. Review
  7. Article
  8. Implementation of standardized feeding pathways for infants with gastroschisis to improve patient outcomes: A quality improvement project in a level IV surgical NICU.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Article
  9. Article
  10. Does time to theater matter in simple gastroschisis?World journal of pediatric surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Donna HobsonGrace Centre for Newborn Care, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.
Kaye SpenceGrace Centre for Newborn Care, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia. Kaye.Spence@health.nsw.gov.au.ORCID 0000-0003-1241-9303
Amit TrivediGrace Centre for Newborn Care, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.
Gordon ThomasThe Children's Hospital at Westmead Clinical School, The University of Sydney, Locked Bag 4001, Westmead, NSW, 2145, Australia.
The University of Sydney · AUChildren's Hospital at Westmead · AUWaterNSW · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to examine differences in attitudes to feeding in neonates with Gastroschisis between clinical groups and to develop a standardized feeding protocol. Confusion, inconsistencies in practice and lack of evidence could be contributing to avoidable delays in the establishment of enteral feeds resulting in lengthy requirements for central venous access, dependence on total parenteral nutrition (TPN), increased risk of sepsis, TPN related cholestasis and prolongation in length of hospital stay.

methodsA national survey of clinicians (neonatologists, neonatal intensive care nurses and paediatric surgeons), looking after neonates with gastroschisis was undertaken to determine differences in feeding practice post repair. In addition, an audit of practice in one hospital was undertaken to examine variations in practices between clinicians. A feeding protocol was then developed using inputs from surgeons and neonatologists.

resultsGastric aspirates and residuals were typically used as indicators of feed readiness and feed tolerance; however, there was very little consistency within and between clinical groups in definitions of tolerance or intolerance of feeds and in how to initiate and progress feeds. A feeding protocol with clear definition of feed readiness and a clear pathway to progression of feeds was developed to help overcome these variations in practice with the possibility that this might reduce the length of stay (LOS) and have other secondary benefits. The protocol included early introduction of enteral feeds particularly direct breast or sucking feeds.

conclusionsWide differences in attitudes to feeding neonates post Gastroschsis repair exist and the need for a consistent protocolized approach was felt. The feeding protocol we developed requires a change of practice and further clinical trials are needed to evaluate its effectiveness.

Indexed as

Attitude of Health PersonnelEnteral NutritionBottle FeedingBreast FeedingGastroschisisHumansInfant, NewbornIntensive Care Units, NeonatalNeonatologistsNurses, NeonatalParenteral Nutrition, TotalSurgeonsTime FactorsEnteralFeedGastroschisisInfantNewbornProtocol

Identifiers

PMID31801489
PMCPMC6894280
OpenAlexW2994181847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.