Evidence map›Paper›PMID 31801262›Full record

ReviewMolecules (Basel, Switzerland)2019

Curcumin and Its Derivatives as Potential Therapeutic Agents in Prostate, Colon and Breast Cancers.

Zintle Mbese, Vuyolwethu Khwaza, Blessing Atim Aderibigbe

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it, 174 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Chemical constituents in the rhizome of Curcuma longa and the pharmacological importance of curcumin hybrids.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Cytotoxicity ofInternational journal of molecular sciences · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Curcumin Administration Routes in Breast Cancer Treatment.International journal of molecular sciences · 2024
    Review
  20. Visible light potentiates rapid cell destruction and death by curcumin in vitro.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zintle MbeseDepartment of Chemistry, University of Fort Hare, Alice Campus, Alice 5700, Eastern Cape, South Africa.
Vuyolwethu KhwazaDepartment of Chemistry, University of Fort Hare, Alice Campus, Alice 5700, Eastern Cape, South Africa.ORCID 0000-0003-4875-1535
Blessing Atim AderibigbeDepartment of Chemistry, University of Fort Hare, Alice Campus, Alice 5700, Eastern Cape, South Africa.
University of Fort Hare · ZA

Funding

National Research Foundation, South Africa NRFSouth African Medical Research Council MRC
6 · The paper itself

Abstract

Cancer is a life-threatening disease and is the second leading cause of death around the world. The increasing threats of drug-resistant cancers indicate that there is an urgent need for the improvement or development of more effective anticancer agents. Curcumin, a phenolic compound originally derived from turmeric plant (

Indexed as

AnimalsAntineoplastic Agents, PhytogenicBreast NeoplasmsColonic NeoplasmsCurcuminDose-Response Relationship, DrugDrug Evaluation, PreclinicalDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHumansMaleProstatic NeoplasmsSignal TransductionStructure-Activity RelationshipAntineoplastic Agents, PhytogenicCurcuminanticancer activitybreast cancercolon cancercurcuminderivatives of curcumindrug resistanceprostate cancer

Identifiers

PMID31801262
PMCPMC6930580
OpenAlexW2991005485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.