Evidence map›Paper›PMID 31801236›Full record

ArticleCells2019

miR-1185-1 and miR-548q Are Biomarkers of Response to Weight Loss and Regulate the Expression of

Marcos Garcia-Lacarte, Maria L Mansego, M Angeles Zulet, J Alfredo Martinez, Fermin I Milagro

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marcos Garcia-LacarteDepartment of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.
Maria L MansegoDepartment of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-8914-7890
M Angeles ZuletDepartment of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3926-0892
J Alfredo MartinezDepartment of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-5218-6941
Fermin I MilagroDepartment of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3228-9916
Instituto de Salud Carlos III · ESUniversidad de Navarra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present investigation was to identify putative miRNAs involved in the response to weight loss. Reverse-transcribed RNA isolated from white blood cells (WBCs) of a subpopulation from the Reduction of the Metabolic Syndrome in Navarra-Spain (RESMENA-S) study (low-responders (LR) and high-responders (HR)) was hybridized in a gene expression microarray. Moreover, miRNAs were sequenced by miRNA-Seq. It was found that miR-548q and miR-1185-1 were overexpressed in HR, both in the microarray and in the miRNA-Seq. A bioinformatic prediction of putative target genes of the selected miRNAs found that

Indexed as

BiomarkersGene Expression RegulationGenetic Association Studies3' Untranslated RegionsBody WeightCell LineComputational BiologyDiet TherapyGene Expression ProfilingGenes, ReporterGlycogen Synthase Kinase 3 betaHumansMicroRNAsRNA InterferenceWeight Loss3' Untranslated RegionsBiomarkersGlycogen Synthase Kinase 3 betaGSK3B protein, humanMicroRNAsMIRN548 microRNA, humanbiomarkerinflammationmicroRNAmiRNA-Seqobesity

Identifiers

PMID31801236
PMCPMC6953011
OpenAlexW2991145074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.