ReviewMaterials (Basel, Switzerland)2019
Current State of Bone Adhesives-Necessities and Hurdles.
Review in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analyses on animal models used in bone adhesive research.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Pooled it
- Wet-adhesive and antibacterial PAH-TPP coacervates with self-mineralizing capability for cranial flap fixation.Bioactive materials · 2025Article
- Bone filler and adhesive at the same time: in-vitro analysis in a porcine fracture model.BMC musculoskeletal disorders · 2025Article
- A magnesium calcium phosphate-based cement as a bone adhesive: characterization and biomechanical evaluation.BMC musculoskeletal disorders · 2025Article
- Degradable polymer bone adhesives.Fundamental research · 2025Review
- A particle-filled hydrogel based on alginate and calcium phosphate nanoparticles as bone adhesive.Journal of materials science. Materials in medicine · 2024Article
- Rheological and Biological Properties of Adhesive Skin Secretions fromScientifica · 2024Article
- Biodegradable Implants for Internal Fixation of Fractures and Accelerated Bone Regeneration.ACS omega · 2023Review
- In Vitro and In Vivo Evaluation of a Bio-Inspired Adhesive for Bone Fixation.Pharmaceutics · 2023Article
- Bone adhesive materials: From bench to bedside.Materials today. Bio · 2023Review
- Percutaneous bone adhesive application for Jones fracture "at-risk" of nonunion or delayed union: a hypothesis.Patient safety in surgery · 2022Article
- Influence of Initiator Concentration on the Polymerization Course of Methacrylate Bone Cement.Polymers · 2022Article
- Biodegradable and Biocompatible Adhesives for the Effective Stabilisation, Repair and Regeneration of Bone.Bioengineering (Basel, Switzerland) · 2022Review
- Cu-Doped Hollow Bioactive Glass Nanoparticles for Bone Infection Treatment.Pharmaceutics · 2022Article
- Long-term efficacy and safety of 3D printed implant in patients with nasal septal deformities.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Article
- A Biosynthetic Hybrid Spidroin-Amyloid-Mussel Foot Protein for Underwater Adhesion on Diverse Surfaces.ACS applied materials & interfaces · 2021Article
- Refined Structures ofThe journal of physical chemistry. B · 2021Article
- Prediction of Lap Shear Strength and Impact Peel Strength of Epoxy Adhesive by Machine Learning Approach.Nanomaterials (Basel, Switzerland) · 2021Article
- Change in Pull-Out Force during Resorption of Magnesium Compression Screws for Osteosynthesis of Mandibular Condylar Fractures.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vision of gluing two bone fragments with biodegradable and biocompatible adhesives remains highly fascinating and attractive to orthopedic surgeons. Possibly shorter operation times, better stabilization, lower infection rates, and unnecessary removal make this approach very appealing. After 30 years of research in this field, the first adhesive systems are now appearing in scientific reports that may fulfill the comprehensive requirements of bioadhesives for bone. For a successful introduction into clinical application, special requirements of the musculoskeletal system, challenges in the production of a bone adhesive, as well as regulatory hurdles still need to be overcome. In this article, we will give an overview of existing synthetic polymers, biomimetic, and bio-based adhesive approaches, review the regulatory hurdles they face, and discuss perspectives of how bone adhesives could be efficiently introduced into clinical application, including legal regulations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.