Evidence map›Paper›PMID 31801095›Full record

ArticleStructure (London, England : 1993)2019

C-lection by the DM15 Motif Gets LARP1 to the TOP.

Mark A Bayfield, Kyra Kerkhofs, Farnaz Mansouri-Noori

Abstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Conserved Functions of LARP1 Proteins in Eukaryotes.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Mark A BayfieldDepartment of Biology, York University, Toronto, ON, Canada. Electronic address: bayfield@yorku.ca.
Kyra KerkhofsDepartment of Biology, York University, Toronto, ON, Canada.
Farnaz Mansouri-NooriDepartment of Biology, York University, Toronto, ON, Canada.

Funding

CIHR
6 · The paper itself

Abstract

LARP1 proteins integrate the translation and stability of 5'TOP mRNAs with signaling from the mTOR pathway, but the mechanism is not well understood. In this issue of Structure, Cassidy et al. (2019) propose that the LARP1-DM15 motif modulates access to the 5'TOP mRNA's m

Indexed as

AutoantigensRibonucleoproteinsRNA, MessengerSignal TransductionAutoantigensRibonucleoproteinsRNA, Messenger

Identifiers

PMID31801095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.