ArticleJournal of applied oral science : revista FOB2020
Comparative effects of final canal irrigation with chitosan and EDTA.
Article in Journal of applied oral science : revista FOB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Antimicrobial Efficacy of Chitosan vs. Sodium Hypochlorite AgainstMedicina (Kaunas, Lithuania) · 2026Pooled it
- Impact of laser-assisted and different pre-treatment modalities on dentin surface interface and bond strength of fiber posts (In-vitro study).Head & face medicine · 2026Article
- Push-out bond strength of biodentine after calcium hydroxide removal using novel chelation-activation protocols in regenerative endodontics.Odontology · 2026Article
- Chitosan Molecular Weight Influences on Endodontic Biofilms and Material Enhancement Strategies.Dentistry journal · 2026Article
- Push-out bond strength evaluation of endodontic bioceramic sealer (Bioroot RCS) after final irrigation with different intracanal irrigants: A comparative in vitro study.Bioinformation · 2026Article
- Impact of Chitosan and Benzalkonium Chloride as Final Irrigants on Fracture Resistance and Surface Roughness of Endodontically Treated Roots: An In Vitro Study.International journal of dentistry · 2026Article
- Evaluation of the Effects of Retro-Cavity Preconditioning with or Without Ethylenediaminetetraacetic Acid on Root Surface pH and Dislodgement Resistance of NeoMTA2 and Mineral Trioxide Aggregate Flow Retro-Fills: An Ex Vivo Investigation.Journal of functional biomaterials · 2024Article
- Pre-Sealing of Endodontic Access Cavities for the Preservation of Anterior Teeth Fracture Resistance.Clinical and experimental dental research · 2024Article
- Comparative Evaluation of the Effect of Different Chelating Agents on Mineral Content and Erosion of Radicular Dentine: A FESEM-EDS Analysis.European endodontic journal · 2024Article
- Article
- Effect of Carbodiimide (EDC) on the Bond Strength Longevity of Epoxy Resin-based Endodontic Sealer to Root Dentin: An In-Vitro Study.The journal of adhesive dentistry · 2023Article
- Antimicrobial efficacy of composite irrigation solution against dominant pathogens in seawater immersion wound andFrontiers in microbiology · 2023Article
- The effects of different root canal irrigation protocols and artificial aging procedures on the bond strength between dentin and hybrid ceramic posts.BMC oral health · 2022Article
- EDTA-chitosan is a feasible conditioning agent for dentin bonding.Clinical oral investigations · 2022Article
- Effects of chitosan-containing silver nanoparticles or chlorhexidine as the final irrigant on the bond strength of resin-based root canal sealers.Journal of dental research, dental clinics, dental prospects · 2022Article
- Nanoparticles in Dentistry: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Time-Dependent Effect of Chitosan Nanoparticles as Final Irrigation on the Apical Sealing Ability and Push-Out Bond Strength of Root Canal Obturation.International journal of dentistry · 2020Article
- Comparative evaluation of push-out bond strength of bioceramic and epoxy sealers after using various final irrigants: AnJournal of conservative dentistry : JCDArticle
- Influence of Various Chelating Irrigating Solutions and Protocols on the Micro-hardness and Surface Roughness of Root Dentin.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
other: Chitosan is a natural, biocompatible chelating substance with potential for dental use. This study compared the effects of final canal irrigation with chitosan and EDTA on dentin microhardness, sealer dentin tubules penetration capacity, and push-out strength. METHODOLOGY: Fifty canine roots were distributed according to the final irrigation protocol (n=10): G1- 15% EDTA with conventional irrigation; G2- 15% EDTA with Endovac; G3- 0.2% chitosan with conventional irrigation; G4- 0.2% chitosan with Endovac; and G5- without irrigation. Specimens were obturated (AH Plus) and sectioned in 3 slices per root third. The first slice was used for microhardness and sealer penetration assessments under a laser confocal microscope. The second was utilized in a push-out strength test. The third slice was discarded. Data were analyzed using 2-way ANOVA and Tukey's post hoc test (α<0.05). Failure mode was determined at x40 magnification.
resultsMicrohardness reduction was more significant in groups G2 and G4 (p<0.05). Sealer penetration through dentin was significantly greater in group G2 (p<0.05). There was no significant difference between groups G1, G3, and G4 (p>0.05). In general, all experimental groups presented similar bond resistance (p>0.05) that significantly differed from the control (p<0.001). Mixed type failures were predominant.
conclusionsIn general, 0.2% chitosan and 15% EDTA solutions act in a similar manner with regard to the variables studied. The use of Endovac potentiates the effect of these solutions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.