ArticlePloS one2019
Risk factors of post-discharge under-five mortality among Danish children 1997-2016: A register-based study.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Pediatric Intensive Care Utilization and Outcomes in Denmark.JAMA network open · 2026Article
- Article
- Association between chronic diseases in childhood and subsequent educational achievement: a Danish register-based cohort study.European journal of epidemiology · 2026Article
- Nationwide registry study of long term survival and comorbidities in total anomalous pulmonary venous connection in Denmark.Scientific reports · 2025Article
- Pediatric health service utilization at tertiary hospitals in Denmark 2000-2018.Scientific reports · 2024Article
- Surgical procedures in Danish children 1999-2018.PloS one · 2023Article
- Socioeconomic background affects mortality in Danish children with severe chronic disease.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- The match between need and use of health services among healthy under-fives in Denmark: A register-based national cohort study.PloS one · 2020Article
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5 authors.
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Abstract
objectivesEstimating associations between somatic and socioeconomic risk factors and post-discharge under-five mortality.
designRegister-based national cohort study using multiple Cox regression.
participantsThe population of 1,263,795 Danish children live-born 1997-2016 who survived until date of first discharge to the home after birth was followed from that date until death, emigration, 5 years of age or 31 December 2016.
main outcome measures(A) Mortality hazard ratios (HRs) among all children, (B) mortality HRs among children without severe chronic disease, and (C) mortality HRs among children without severe chronic disease or asthma. MAIN
resultsIn the total population (1,947 deaths) severe chronic disease was associated with mortality HR = 15.28 (95% CI: 13.77-16.95). In children without severe chronic-disease (719 deaths) other somatic risk factors were immature birth HR = 3.40 (1.92-6.02), maternal smoking HR = 1.84 (1.55-2.18) and low birth weight HR = 1.74 (1.21-2.51). Socioeconomic risk factors for mortality included: maternal age < 25 years HR = 1.91 (1.38-2.64) compared to > 35 years (similar for 30-35 years and 25-29 years), lowest vs. highest family income tertile HR = 1.76 (1.23-2.51), not living with both parents HR = 1.63 (1.25-2.13), maternal unemployment HR = 1.54 (1.12-2.12), presence of siblings HR = 1.44 (1.20-1.71) and secondary vs. tertiary parental education HR = 1.33 (1.07-1.65) for fathers and HR = 1.23 (1.01-1.52) for mothers. Factors not found to be associated with child mortality in this population included presence of asthma HR = 1.29 (0.83-1.98) and non-Danish ethnicity HR = 0.98 (0.70-1.37).
conclusionsChildhood death after discharge to the home after birth and before 5 years of age is a very rare event in Denmark. This 'post-discharge' mortality was heavily associated with severe chronic disease. In children without severe chronic disease, immature birth, maternal smoking and certain socioeconomic characteristics were noticeable risk factors. Mortality may possibly be decreased by focusing on vulnerable groups.
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