ReviewJournal of neurophysiology2020
A review of efferent cholinergic synaptic transmission in the vestibular periphery and its functional implications.
Review in Journal of neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed.
- Seasickness, Sea Legs, and Gravity: Suppression of Motion Sickness, Development of Sea Legs, The Role of the Striated Organelle in the Vestibular Efferent System.Audiology research · 2026Article
- Selective genetic targeting of the mouse efferent vestibular nucleus identifies monosynaptic inputs and indicates function as multimodal integrator.Journal of neurophysiology · 2026Article
- Neurotransmitter regulatory networks in persistent postural-perceptual dizziness: potential mechanisms and therapeutic implications.Frontiers in neurology · 2026Review
- Perspective: Hippocampal theta rhythm as a potential vestibuloacoustic biomarker of anxiety.The European journal of neuroscience · 2025Review
- Assessment of the Interaction of Acetylcholinesterase Binding with Bioactive Compounds from Coffee and Coffee Fractions DigestedJournal of agricultural and food chemistry · 2024Article
- A New Perspective to Interpret How the Vestibular Efferent System Correlates the Complexity of Routine Balance Maintenance with Management of Emergency Fall Prevention Strategies.Audiology research · 2024Article
- Alpha9alpha10 knockout mice show altered physiological and behavioral responses to signals in masking noise.The Journal of the Acoustical Society of America · 2024Article
- Aged mice are less susceptible to motion sickness and show decreased efferent vestibular activity compared to young adults.Brain and behavior · 2023Article
- Molecular and Functional Changes to Postsynaptic Cholinergic Signaling in the Vestibular Sensory Organs of Aging C57BL/6 Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Untargeted metabolomics of the cochleae from two laryngeally echolocating bats.Frontiers in molecular biosciences · 2023Article
- Vestibulo-Ocular Reflex Short-Term Adaptation Is Halved After Compensation for Unilateral Labyrinthectomy.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Functional and ultrastructural analysis of reafferent mechanosensation in larval zebrafish.Current biology : CB · 2022Article
- Using Light-Sheet Microscopy to Study Spontaneous Activity in the Developing Lateral-Line System.Frontiers in cell and developmental biology · 2022Article
- Editorial: Commonalities and Differences in Vestibular and Auditory Pathways.Frontiers in neuroscience · 2022Article
- Simultaneous Dual Recordings From Vestibular Hair Cells and Their Calyx Afferents Demonstrate Multiple Modes of Transmission at These Specialized Endings.Frontiers in neurology · 2022Review
- Article
- The mammalian efferent vestibular system utilizes cholinergic mechanisms to excite primary vestibular afferents.Scientific reports · 2021Article
- Loss of α-9 Nicotinic Acetylcholine Receptor Subunit Predominantly Results in Impaired Postural Stability Rather Than Gaze Stability.Frontiers in cellular neuroscience · 2021Article
- Cholinergic Modulation of Membrane Properties of Calyx Terminals in the Vestibular Periphery.Neuroscience · 2021Article
- Differences in the Structure and Function of the Vestibular Efferent System Among Vertebrates.Frontiers in neuroscience · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
It has been over 60 years since peripheral efferent vestibular terminals were first identified in mammals, and yet the function of the efferent vestibular system remains obscure. One reason for the lack of progress may be due to our deficient understanding of the peripheral efferent synapse. Although vestibular efferent terminals were identified as cholinergic less than a decade after their anatomical characterization, the cellular mechanisms that underlie the properties of these synapses have had to be inferred. In this review we examine how recent mammalian studies have begun to reveal both nicotinic and muscarinic effects at these terminals and therefore provide a context for fast and slow responses observed in classic electrophysiological studies of the mammalian efferent vestibular system, nearly 40 years ago. Although incomplete, these new results together with those of recent behavioral studies are helping to unravel the mysterious and perplexing action of the efferent vestibular system. Armed with this information, we may finally appreciate the behavioral framework in which the efferent vestibular system operates.
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