ArticleCerebral cortex (New York, N.Y. : 1991)2020
Using the Principles of Multisensory Integration to Reverse Hemianopia.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Audio-visual stimulation for visual compensatory functions in stroke survivors with visual field defect: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Pooled it
- A telerehabilitation program to improve visual perception in children and adolescents with hemianopia consecutive to a brain tumor: a single-arm feasibility and proof-of-concept trial.EClinicalMedicine · 2024Article
- The brain can develop conflicting multisensory principles to guide behavior.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cross-modal exposure restores multisensory enhancement after hemianopia.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Ameliorating Hemianopia with Multisensory Training.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Noise-rearing precludes the behavioral benefits of multisensory integration.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Review
- Association Cortex Is Essential to Reverse Hemianopia by Multisensory Training.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- An Audiovisual 3D-Immersive Stimulation Program in Hemianopia Using a Connected Device.The American journal of case reports · 2021Article
- Using superior colliculus principles of multisensory integration to reverse hemianopia.Neuropsychologia · 2020Article
- A Multidimensional, Multisensory and Comprehensive Rehabilitation Intervention to Improve Spatial Functioning in the Visually Impaired Child: A Community Case Study.Frontiers in neuroscience · 2020Article
- Reversing Hemianopia by Multisensory Training Under Anesthesia.Frontiers in systems neuroscience · 2020Article
- Interhemispheric visual competition after multisensory reversal of hemianopia.The European journal of neuroscience · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Hemianopia can be rehabilitated by an auditory-visual "training" procedure, which restores visual responsiveness in midbrain neurons indirectly compromised by the cortical lesion and reinstates vision in contralesional space. Presumably, these rehabilitative changes are induced via mechanisms of multisensory integration/plasticity. If so, the paradigm should fail if the stimulus configurations violate the spatiotemporal principles that govern these midbrain processes. To test this possibility, hemianopic cats were provided spatially or temporally noncongruent auditory-visual training. Rehabilitation failed in all cases even after approximately twice the number of training trials normally required for recovery, and even after animals learned to approach the location of the undetected visual stimulus. When training was repeated with these stimuli in spatiotemporal concordance, hemianopia was resolved. The results identify the conditions needed to engage changes in remaining neural circuits required to support vision in the absence of visual cortex, and have implications for rehabilitative strategies in human patients.
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Registered trials
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