Evidence map›Paper›PMID 31799463›Full record

ArticleHeliyon2019

Detection and molecular characterization of porcine parvovirus in fetal tissues from sows without reproductive failure in Argentina.

M S Serena, J A Cappuccio, G E Metz, C G Aspitia, M Dibárbora, M Gallo Calderón, M G Echeverría

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

M S SerenaLaboratorio de Virología, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calles 60 y 118, 1900, La Plata, Argentina.
J A CappuccioInvestigadores del Consejo Nacional de Ciencia y Tecnología, CONICET, Argentina.
G E MetzLaboratorio de Virología, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calles 60 y 118, 1900, La Plata, Argentina.
C G AspitiaLaboratorio de Virología, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calles 60 y 118, 1900, La Plata, Argentina.
M DibárboraGrupo Sanidad Animal, EEA Marcos Juarez, INTA. Ruta 12 km 3 (2580) Marcos Juarez, Córdoba, Argentina.
M Gallo CalderónInvestigadores del Consejo Nacional de Ciencia y Tecnología, CONICET, Argentina.
M G EcheverríaLaboratorio de Virología, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calles 60 y 118, 1900, La Plata, Argentina.
Universidad Nacional de La Plata · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARHospital César Milstein · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine parvovirus (PPV) is one of many pathogens responsible for reproductive failure in pregnant sows. Several studies have reported the appearance of new PPV strains that differ from previous isolates both genetically and antigenically. Thus, the protective effects of commercially inactivated vaccines could not be complete. In South America, the information about PPV is limited. Thus, the aim of the present study was to detect and characterize the PPV strains present in 131 mummies or stillbirths from normal deliveries in sows from a commercial swine farm of Argentina that uses the commercial vaccine. PCR results showed that 17/131 were positive to PPV. Ten of these viruses were isolated and sequenced. All viruses were related to the PPV1 sequence (NADL-2), maintaining the amino acid differences in positions 436 (S-P) and 565 (R-K). This study is the first to report the isolation of PPV in Argentina and the results suggest that PPV can cross the placenta even in vaccinated sows, thus affecting some of the fetuses and being able to cause fetal death in sows without reproductive failure. The results also suggest that vaccination only reduces clinical signs and reproductive disorders and may thus not be a perfect tool to manage PPV infection. This study provides information that needs to be studied in depth to improve strategies to prevent and control PPV infection in swine farms.

Indexed as

BiotechnologyImmunologyMicrobiologyMolecular biologyMolecular characterizationPorcine parvovirusReproductive failuresVeterinary medicine

Identifiers

PMID31799463
PMCPMC6881615
OpenAlexW2991177931

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.