ArticleCommunications biology2019
Evaluation of human obstructive sleep apnea using computational fluid dynamics.
Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- The effect of mandibular advancement with clear aligners compared with activator therapy on maxillary and mandibular volumes: a randomized controlled trial using CBCT.BMC oral health · 2026Trial
- Application of numerical simulation of upper airway flow field in pediatric obstructive sleep apnea with adenoid hypertrophy.Quantitative imaging in medicine and surgery · 2026Article
- CT and finite element analysis of mandibular advancement device mechanics in a participant with obstructive sleep apnea: a proof-of-concept study.BMC oral health · 2026Article
- Obstructive Sleep Apnea and Cardiovascular Disease: Mechanisms, Diagnostics, and Emerging Therapeutic Approaches.Biomedicines · 2026Review
- Simulation of Central Airway Gas Flow Dynamics During Conventional and Multifrequency Ventilation.Journal of biomechanical engineering · 2025Article
- Numerical simulation and functional evaluation of upper airway before and after twin block treatment with different respiratory pathways.Clinical oral investigations · 2025Article
- Efficacy comparison between dentofacial orthopedic treatment and adenotonsillectomy on children with obstructive sleep apnea and skeletal class II malocclusion: a retrospective study.BMC oral health · 2025Article
- Mechanistic Analysis of Fluid Dynamics and Multifactorial Impact Mechanisms in Inhaled Pharmaceutical Deposition for Chronic Respiratory Diseases.Bioengineering (Basel, Switzerland) · 2025Article
- Investigation of the physical driving mechanisms of wind noise in hearing devices by computational fluid dynamics.Scientific reports · 2025Article
- Analysis of upper airway CT-based radiomics in adult obstructive sleep apnea.Frontiers in medicine · 2025Article
- Computational multiphysics modeling of radioactive aerosol deposition in diverse human respiratory tract geometries.Communications engineering · 2024Article
- Modeling Realistic Geometries in Human Intrathoracic Airways.Diagnostics (Basel, Switzerland) · 2024Review
- Automatic prediction of obstructive sleep apnea in patients with temporomandibular disorder based on multidata and machine learning.Scientific reports · 2024Article
- Analysis of the aerodynamic characteristics of the upper airway in obstructive sleep apnea patients.Journal of dental sciences · 2024Article
- Effects of 3D Airway Geometry on the Airflow of Adults with Cleft Lip and Palate and Obstructive Sleep Apnea: A Functional Imaging Study.Sleep science (Sao Paulo, Brazil) · 2023Article
- Upper Airway Flow Dynamics in Obstructive Sleep Apnea Patients with Various Apnea-Hypopnea Index.Life (Basel, Switzerland) · 2022Article
- The influence of mouth opening on pharyngeal pressure loss and its underlying mechanism: A computational fluid dynamic analysis.Frontiers in bioengineering and biotechnology · 2022Article
- What is the impact of distraction osteogenesis on the upper airway of hemifacial microsomia patient with obstructive sleep apnea: a case report.European journal of medical research · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) severity might be correlated to the flow characteristics of the upper airways. We aimed to investigate the severity of OSA based on 3D models constructed from CT scans coupled with computational fluid dynamics (CFD) simulations. The CT scans of seven adult patients diagnosed with OSA were used to reconstruct the 3D models of the upper airways and CFD modeling and analyses were performed. Results from the fluid simulations were compared with the apnea-hypopnea index. Here we show a correlation between a CFD-based parameter, the adjusted pressure coefficient (Cp*), and the respective apnea-hypopnea index (Pearson's r = 0.91, p = 0.004), which suggests that the anatomical-based model coupled with CFD could provide functional and localized information for different regions of the upper airways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.