ArticleData in brief2019
Data on the inhibitory effect of endophytic fungi of traditional medicinal plants against pancreatic lipase (PL).
Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 7 citations in OpenAlex.
- Nutraceutic Potential of Bioactive Compounds ofMolecules (Basel, Switzerland) · 2022Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article describes isolation and pancreatic lipase (PL) inhibitory potential of 18 endophytic fungi isolated from the various parts of six indigenous medicinal plants. PL catalyzes absorption and hydrolysis of triglycerides into di-glycerides into mono-glycerides and free fatty acids. PL inhibitors are well-known for the disruption of pancreatic lipase activity. The quest for novel pancreatic lipase inhibitors is crucially important owing to their therapeutic potential in the treatment of obesity and related chronic diseases. The present dataset provides information about the presence of endophytic fungi in the internal tissues of selected plants and the PL inhibitory potential of their metabolites using bioassay based screening. Absence of the yellow zone surrounding the standard Orlistat and test extract indicated PL inhibition due to the cumulative effect of metabolites present in the extract. The data suggests that TLC bio-autographic method is simple, rapid and reproducible and therefore it could be effectively used for high throughput screening of PL inhibitors from natural sources.
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