Evidence map›Paper›PMID 31799298›Full record

ArticleWorld journal of clinical cases2019

End-stage liver disease score and future liver remnant volume predict post-hepatectomy liver failure in hepatocellular carcinoma.

Fan-Hua Kong, Xiong-Ying Miao, Heng Zou, Li Xiong, Yu Wen, Bo Chen, Xi Liu, Jiang-Jiao Zhou

Open access · diamondAbstract read
In one paragraph

Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Emerging Roles of mFrontiers in oncology · 2022
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  20. The roles of RNA NHeliyon · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fan-Hua KongDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Xiong-Ying MiaoDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Heng ZouDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Li XiongDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Yu WenDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Bo ChenDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Xi LiuDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.
Jiang-Jiao ZhouDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China. zhoujiangjiao@csu.edu.cn.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatocellular carcinoma (HCC) is the world's sixth most common malignant tumor and the third cause of cancer death. Although great progress has been made in hepatectomy, it is still associated with a certain degree of risk of post-hepatectomy liver failure (PHLF), which extends the length of hospital stay and remains the leading cause of postoperative death. Studies have shown that assessment of hepatic functional reserve before hepatectomy is beneficial for reducing the incidence of PHLF.

aimTo assess the value of model for end-stage liver disease (MELD) score combined with standardized future liver remnant (sFLR) volume in predicting PHLF in patients undergoing hepatectomy for HCC.

methodsThis study was attended by 238 patients with HCC who underwent hepatectomy between January 2015 and January 2018. Discrimination of sFLR volume, MELD score, and sFLR/MELD ratio to predict PHLF was evaluated according to the area under the receiver operating characteristic curve.

resultsThe patients were divided into two groups according to whether PHLF occurred after hepatectomy. The incidence of PHLF was 8.4% in our research. The incidence of PHLF increased with the decrease in sFLR volume and the increase in MELD score. Both sFLR volume and MELD score were considered independent predictive factors for PHLF. Moreover, the cut-off value of the sFLR/MELD score to predict PHLF was 0.078 (

conclusionMELD combined with sFLR is a reliable and effective PHLF predictor, which is superior to MELD score or sFLR volume alone.

Indexed as

HepatectomyHepatitis B virusHepatocellular carcinomaModel for end-stage liver diseasePost-hepatectomy liver failureStandardized future liver remnant

Identifiers

PMID31799298
PMCPMC6887604
OpenAlexW2989618538

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.