ArticleSkin appendage disorders2019
Nail Involvement during Pemphigus.
Article in Skin appendage disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Nail Involvement in Pemphigus: A Clinical and Dermoscopic Prospective Study.Skin appendage disorders · 2025Article
- Current Knowledge on Nail Involvement in Autoimmune Bullous Disorders.Skin appendage disorders · 2024Review
- Article
- [Hailey-Hailey disease: A case report].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Nail Loss in Mild to Moderate Pemphigus Vulgaris.Skin appendage disorders · 2022Article
- Nail changes in pemphigus and bullous pemphigoid: A single-center study in China.Frontiers in medicine · 2022Article
- Nail Changes in Immuno-Bullous Disorders: A Cross-Sectional Study.Indian journal of dermatologyArticle
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPemphigus is an autoimmune bullous disease affecting the skin and mucous membranes. Associated nail involvement is underestimated and is characterized by a variety of clinical manifestations. Our aim was to describe the clinical aspects of nail involvement during pemphigus. PATIENTS AND
methodsA retrospective study was conducted of patients with pemphigus over a period of 12 years. The diagnosis of pemphigus was based on clinical and immunopathological data. Clinical data were collected from patient records prior to initiation of treatment.
resultsOverall,141 cases of pemphigus were collected. Of these, 60 patients had nail involvement. After eliminating fungal origin, we selected 37 patients in our study. The main clinical forms were paronychia and dystrophy. Two cases of destruction of the nail apparatus were found in patients with pemphigus vegetans. The disease was bilateral in 11 cases (29.7%). The presence of ungual involvement was correlated with severity of pemphigus, particularly severe oral disease (
conclusionNail lesions were polymorphic in our patients. These signs show accumulated inflammation of the nail after a long evolution of the disease. Nail involvement may precede, be concomitant, or follow the mucocutaneous lesions of pemphigus and be a sign of severity or relapse of the disease.
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