Evidence map›Paper›PMID 31799259›Full record

ArticleSkin appendage disorders2019

Precision Medicine and the Practice of Trichiatry: Adapting the Concept.

Ralph M Trüeb, Vicky M L Jolliffe, Antonia Fellas Régnier, Hudson Dutra Rezende, Sergio Vañó-Galván, Daisy Kopera, Demetrios Ioannides, Maria Fernanda Reis Gavazzoni Dias, Melanie Macpherson, Aida Gadzhigoroeva and 6 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Skin appendage disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. A Comment on Posing in Medicine.International journal of trichology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 13 institutions in 13 countries.

Ralph M TrüebCenter for Dermatology and Hair Diseases Professor Trüeb, University of Zurich, Zurich, Switzerland.
Vicky M L JolliffeThe Royal London Hospital, London, United Kingdom.
Antonia Fellas RégnierCenter for Dermatology and Hair Diseases Professor Trüeb, University of Zurich, Zurich, Switzerland.
Hudson Dutra RezendeCenter for Dermatology and Hair Diseases Professor Trüeb, University of Zurich, Zurich, Switzerland.
Sergio Vañó-GalvánRamon y Cajal Hospital, University of Alcala, Madrid, Spain.
Daisy KoperaCenter of Aesthetic Medicine, Department of Dermatology, Medical University Graz, Graz, Austria.
Demetrios Ioannides1st Department of Dermatology-Venereology, Aristotle University Medical School, Hospital of Skin and Venereal Diseases, Thessaloniki, Greece.
Maria Fernanda Reis Gavazzoni DiasDepartment of Dermatology, Centro de Ciências Médicas, Hospital Universitário Antonia Pedro, Universidade Federal Fluminense, Niterói, Brazil.
Melanie MacphersonDepartment of Dermatology and Venereology, San Gabriel Clinic, Lima, Peru.
Aida GadzhigoroevaMoscow Scientific and Practical Center of Dermatology and Cosmetology of the Moscow City Health Department, Moscow, Russian Federation.
Julya OvcharenkoGeneral and Clinical Immunology and Allergology Department, School of Medicine, V.N. Karazin Kharkiv National University, Kharkiv, Ukraine.
Won-Soo LeeDepartment of Dermatology, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.
Sundaram MurugusundramChennai Skin Foundation & Yesudian Research Institute, Chennai, India.
Sotaro KurataBeppu Garden Hill Clinic & Kurata Clinic, Beppu City, Japan.
Mimi ChangPrince of Wales Hospital and the Chinese University of Hong Kong, Hong Kong, China.
Chuchai TanglertsampanDepartment of Dermatology, Mae Fah Luang University Hospital (Bangkok), Bumrungrad International Hospital, Bangkok, Thailand.
University of Zurich · CHBumrungrad International Hospital · THChennai Skin Foundation & Yesudian Research Institute · INChinese University of Hong Kong · CNHospital Universitário Antônio Pedro · BRHospital Venereal and Skin Diseases Thessaloniki · GRMedical University of Graz · ATMurata (Japan) · JPRoyal London Hospital · GBState Research Center for Dermatovenereology and Cosmetology · RUUniversidad de Alcalá · ESV. N. Karazin Kharkiv National University · UAYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence-based medicine (EBM) aims for the ideal that healthcare professionals make conscientious, explicit, and judicious use of the best available evidence gained from the scientific method to clinical decision-making. It seeks to assess the strength of the evidence for benefits of diagnostic tests and treatments, using techniques from science, engineering, and statistics, such as the systematic review of medical literature, meta-analysis, risk-benefit analysis, and randomized controlled trials. The limited success rate of EBM therapies suggests that the complex nature of hair loss may be inadequately served by the present levels of evidence, and that physicians treating hair loss may have fallen short of adequately researching a robust evidence to underpin their practices. Against this backdrop, the concept of precision medicine (PM) is evolving. PM refers to the customization of medical care to the patient's individual characteristics based on the patient's genetic background and other molecular or cellular analysis, while classifying patients into subpopulations that differ in their susceptibility to a particular medical condition, in the biology or prognosis of those medical conditions, or in their response to a specific treatment. With the advances in hair research, the powerful tools of molecular biology and genetics, and innovative technologies, we have the robust scientific data and tools to adapt the concept of PM to the practice of trichiatry. Finally, databases pertaining to the development and efficacy of PM must be analyzed and be used to form the basis of evidence-based personalized trichiatry.

Indexed as

ComorbidityPanomicsPrecision medicineTargeted therapiesTrichiatry

Identifiers

PMID31799259
PMCPMC6883441
OpenAlexW2976745978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.