Evidence map›Paper›PMID 31799246›Full record

ReviewFrontiers in bioengineering and biotechnology2019

Theranostic Nanomedicine for Malignant Gliomas.

Michele d'Angelo, Vanessa Castelli, Elisabetta Benedetti, Andrea Antonosante, Mariano Catanesi, Reyes Dominguez-Benot, Giuseppina Pitari, Rodolfo Ippoliti, Annamaria Cimini

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 44 citations in OpenAlex.

  1. Advancements in nanotheranostics for glioma therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2025
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  17. International journal of nanomedicine · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Michele d'AngeloDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Vanessa CastelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Elisabetta BenedettiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Andrea AntonosanteDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Mariano CatanesiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Reyes Dominguez-BenotDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Giuseppina PitariDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Rodolfo IppolitiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Annamaria CiminiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
University of L'Aquila · ITTemple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain tumors mainly originate from glial cells and are classified as gliomas. Malignant gliomas represent an incurable disease; indeed, after surgery and chemotherapy, recurrence appears within a few months, and mortality has remained high in the last decades. This is mainly due to the heterogeneity of malignant gliomas, indicating that a single therapy is not effective for all patients. In this regard, the advent of theranostic nanomedicine, a combination of imaging and therapeutic agents, represents a strategic tool for the management of malignant brain tumors, allowing for the detection of therapies that are specific to the single patient and avoiding overdosing the non-responders. Here, recent theranostic nanomedicine approaches for glioma therapy are described.

Indexed as

brain tumorsdiagnosisdrug deliverytargeted therapytheranostic nanoplatform

Identifiers

PMID31799246
PMCPMC6868071
OpenAlexW2985447739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.