Evidence map›Paper›PMID 31799112›Full record

ArticleJournal of bone oncology2019

Evaluating the scope of intramedullary invasion of malignant bone tumor by DCE-MRI quantitative parameters in animal study.

Yuan Zhang, Yiqing Tan, Cheng Dong, Sai Gao, Wenjian Xu, Haisong Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of bone oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuan ZhangDepartment of Radiology, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, 430000, Hubei, China.
Yiqing TanDepartment of Radiology, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, 430000, Hubei, China.
Cheng DongDepartment of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Sai GaoDepartment of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Wenjian XuDepartment of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Haisong ChenDepartment of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Qingdao University · CNWuhan Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose was to analyze the value of quantitative parameters of DCE-MRI in evaluating micro-infiltration of malignant bone tumors.

methodsThirty-nine New Zealand white rabbits were used to establish malignant bone tumor models by implanting VX2 tumor fragments into the right tibiae. After three weeks, models were examined by conventional MRI and DCE-MRI; then the right tibiae were cut into sagittal sections and partitioned into histology slices for comparison with microscopic findings. Micro-infiltration groups were selected and the range of infiltration was determined under the microscope, and corresponding DCE images analyzed to obtain the quantitative parameters include

results22 cases (22/39, 56.4%) were included in the micro-infiltration group and the infiltration depth ranged from 1.3 mm to 4.6 mm, with an average depth of 3.2 mm ± 0.8 mm. The statistical results of quantitative parameters in the three areas were as follows:

conclusionQuantitative parameters

Indexed as

AUC, area under curveDCE-MRI, dynamic contrast-enhanced magnetic resonance imagingDynamic contrast enhancement magnetic resonance imaging (DCE-MRI)Intramedullary invasionMicro-infiltrationROC, receiver operating characteristic curveVX2 tumor

Identifiers

PMID31799112
PMCPMC6881657
OpenAlexW2991586788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.