Evidence map›Paper›PMID 31799062›Full record

ArticleOpen journal of obstetrics and gynecology2019

Persistent Zika Virus Infection Associated with Early Fetal Demise: A Case Report.

Janice Pérez-Padilla, Gabriela Paz-Bailey, Dana Meaney-Delman, Kate Doyle, Joy Gary, Dania M Rodriguez, Julu Bhatnagar, Nicole M Pérez-Rodriguez, Sara Montalvo, Luisa Alvarado and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Open journal of obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Janice Pérez-PadillaCenters for Disease Control and Prevention (CDC), Dengue Branch, San Juan, Puerto Rico.
Gabriela Paz-BaileyCenters for Disease Control and Prevention (CDC), Dengue Branch, San Juan, Puerto Rico.
Dana Meaney-DelmanCDC, National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA, USA.
Kate DoyleCDC, Division of HIV/AIDS Prevention, Atlanta, GA, USA.
Joy GaryCDC, Infectious Disease Pathology Branch, Atlanta, GA, USA.
Dania M RodriguezCenters for Disease Control and Prevention (CDC), Dengue Branch, San Juan, Puerto Rico.
Julu BhatnagarCDC, Infectious Disease Pathology Branch, Atlanta, GA, USA.
Nicole M Pérez-RodriguezPonce Health Sciences University/Saint Luke's Episcopal Hospital, Ponce, Puerto Rico.
Sara MontalvoPonce Health Sciences University/Saint Luke's Episcopal Hospital, Ponce, Puerto Rico.
Luisa AlvaradoPonce Health Sciences University/Saint Luke's Episcopal Hospital, Ponce, Puerto Rico.
Tyler M SharpCenters for Disease Control and Prevention (CDC), Dengue Branch, San Juan, Puerto Rico.
Ponce Health Sciences University · PRCDC Foundation · USCenters for Disease Control and Prevention · USPuerto Rico Department of Health · PRNational Center for Emerging and Zoonotic Infectious Diseases · USNational Center for HIV/AIDS Viral Hepatitis STD and TB Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundInfection with Zika virus (ZIKV) during pregnancy is known to cause birth defects and could also be linked to pregnancy loss. CASE: A pregnant woman in Puerto Rico contracted ZIKV at 16 weeks gestation. ZIKV RNA persisted in serum from her initial test at 16 weeks through 24 weeks gestation, when fetal demise occurred, and was detected in placental tissue.

conclusionProlonged detection of ZIKV RNA in maternal serum was associated with ZIKV RNA detection in the placenta of a patient who experienced fetal demise. While detection of placenta ZIKV RNA does not establish that ZIKV conclusively caused the demise, these findings support emerging evidence that the placenta may serve as a reservoir for ZIKV, which may be associated with prolonged detection of ZIKV RNA in serum.

Indexed as

Pregnancy OutcomesZikaZIKV Persistence

Identifiers

PMID31799062
PMCPMC6889876
OpenAlexW2946036669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.