ArticleBiomedical optics express2019
Signal averaging improves signal-to-noise in OCT images: But which approach works best, and when?
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed.
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- A large-scale coherent 4D imaging sensor.Nature · 2026Article
- Impact of 85 kHz versus 125 kHz SHIFT OCTA scan speeds on image quality in retinal diseases and diagnostic reliability of choroidal neovascular membranes.Scientific reports · 2025Article
- Impact of image averaging on choroidal quantification using swept-source optical coherence tomography.BMC ophthalmology · 2025Article
- Recent Optical Coherence Tomography (OCT) Innovations for Increased Accessibility and Remote Surveillance.Bioengineering (Basel, Switzerland) · 2025Review
- Article
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- Fast optical coherence tomography angiography image acquisition and reconstruction pipeline for skin application.Biomedical optics express · 2023Article
- Precision of attenuation coefficient measurements by optical coherence tomography.Journal of biomedical optics · 2022Article
- High-Speed Balanced-Detection Visible-Light Optical Coherence Tomography in the Human Retina Using Subpixel Spectrometer Calibration.IEEE transactions on medical imaging · 2022Article
- Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system.Biomedical optics express · 2022Article
- Time-domain signal averaging to improve microparticles detection and enumeration accuracy in a microfluidic impedance cytometer.Biotechnology and bioengineering · 2021Article
- Resolution-enhanced OCT and expanded framework of information capacity and resolution in coherent imaging.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The high acquisition speed of state-of-the-art optical coherence tomography (OCT) enables massive signal-to-noise ratio (SNR) improvements by signal averaging. Here, we investigate the performance of two commonly used approaches for OCT signal averaging. We present the theoretical SNR performance of (a) computing the average of OCT magnitude data and (b) averaging the complex phasors, and substantiate our findings with simulations and experimentally acquired OCT data. We show that the achieved SNR performance strongly depends on both the SNR of the input signals and the number of averaged signals when the signal bias caused by the noise floor is not accounted for. Therefore we also explore the SNR for the two averaging approaches after correcting for the noise bias and, provided that the phases of the phasors are accurately aligned prior to averaging, then find that complex phasor averaging always leads to higher SNR than magnitude averaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.