Evidence map›Paper›PMID 31798940›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

ABO blood group distributions in multiple sclerosis patients from Basque Country; O

Itziar Lopetegi, Amaia Muñoz-Lopetegi, Maialen Arruti, Alvaro Prada, Sabin Urcelay, Javier Olascoaga, David Otaegui, Tamara Castillo-Triviño

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. ABO Blood Group and the Risk and Prognosis of Lymphoma.Journal of inflammation research · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Itziar LopetegiMultiple sclerosis Group, Biodonostia Health Research Institute, Spain.
Amaia Muñoz-Lopetegi
Maialen ArrutiNeurology department, Hospital Universitario Donostia, Spain.
Alvaro PradaImmunology Department, Hospital Universitario Donostia, Spain.
Sabin UrcelayBasque center for transfusion and human tissues, Spain.
Javier OlascoagaMultiple sclerosis Group, Biodonostia Health Research Institute, Spain.
David OtaeguiMultiple sclerosis Group, Biodonostia Health Research Institute, Spain.ORCID https://orcid.org/0000-0002-6625-5976
Tamara Castillo-TriviñoMultiple sclerosis Group, Biodonostia Health Research Institute, Spain.
Spanish Multiple Sclerosis Network · ESDonostiako Unibertsitate Ospitalea · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relation between ABO/Rh groups and multiple sclerosis (MS) has been proposed in several studies, however there is a controversy about the role of these groups in the disease. Although it has been reported that some groups can be protective or risk factors, there is no consensus and discordant reports can be found in the literature. OBJECTIVES AND METHODOLOGY: In this short report, we analyze the ABO/Rh distribution in a MS cohort of 265 patients and compare these frequencies with the results obtained from the Basque Blood Donors bank (17,796 individuals) of the same region. RESULTS AND

conclusionsFrom our data, the absence of immune antigens (A, B or Rhesus +) defined by the group O- seems to be protective in the MS group with an odds ratio of 0.49 (95% confidence interval 0.309-0.796), while the presence of Rh+ plus A or B seems to be a risk in developing multiple sclerosis.

Indexed as

Biomarkersgeneticsimmunologymultiple sclerosis

Identifiers

PMID31798940
PMCPMC6859684
OpenAlexW2987250479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.