Evidence map›Paper›PMID 31798936›Full record

ReviewTropical diseases, travel medicine and vaccines2019

Impact of Endemic Infections on HIV Susceptibility in Sub-Saharan Africa.

Sergey Yegorov, Vineet Joag, Ronald M Galiwango, Sara V Good, Brenda Okech, Rupert Kaul

Open access · goldAbstract readReview
In one paragraph

Review in Tropical diseases, travel medicine and vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Coinfection of HIV-1 withEC microbiology · 2021
    Article
  8. Article
  9. The Role of Dendritic Cells in TB and HIV Infection.Journal of clinical medicine · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Sergey Yegorov1Departments of Immunology and Medicine, University of Toronto, Toronto, Canada.ORCID 0000-0002-7136-7921
Vineet Joag3Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN USA.
Ronald M Galiwango1Departments of Immunology and Medicine, University of Toronto, Toronto, Canada.
Sara V Good4Genetics & Genome Biology, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, ON Canada.
Brenda Okech6UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.
Rupert Kaul1Departments of Immunology and Medicine, University of Toronto, Toronto, Canada.
University of Toronto · CAInternational AIDS Vaccine Initiative · USManitoba Health · CAUniversity Health Network · CAUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) remains a leading cause of global morbidity with the highest burden in Sub-Saharan Africa (SSA). For reasons that are incompletely understood, the likelihood of HIV transmission is several fold higher in SSA than in higher income countries, and most of these infections are acquired by young women. Residents of SSA are also exposed to a variety of endemic infections, such as malaria and various helminthiases that could influence mucosal and systemic immunology. Since these immune parameters are important determinants of HIV acquisition and progression, this review explores the possible effects of endemic infections on HIV susceptibility and summarizes current knowledge of the epidemiology and underlying immunological mechanisms by which endemic infections could impact HIV acquisition. A better understanding of the interaction between endemic infections and HIV may enhance HIV prevention programs in SSA.

Indexed as

helminthiasesHIV risk factorsHIV susceptibilitylymphatic filariasismalariaparasitic infectionsschistosomiasisSub-Saharan Africa

Identifiers

PMID31798936
PMCPMC6884859
OpenAlexW2990800756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.