ArticleJournal of nutritional science2019
Changes in human gut microbiota composition are linked to the energy metabolic switch during 10 d of Buchinger fasting.
Article in Journal of nutritional science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
FastForward: A Prospective Analysis of Long-term Fasting and Subsequent Food Reintroduction in Humans
Preoperative Metabolic Optimization: Influence of Intermittent and Buchinger-Type Fasting on the Gut Microbiome, Immune Profile, and Postoperative Complications in Patients Undergoing Primary Total Hip Arthroplasty - A Randomized Controlled Trial
Who cites it
47 citing papers in PubMed, 77 citations in OpenAlex.
- Machine learning identifies microbiome and clinical predictors of sustained weight loss following prolonged fasting.Genome medicine · 2026Trial
- Five Days Periodic Fasting Elevates Levels of Longevity RelatedInternational journal of molecular sciences · 2021Trial
- Intermittent Fasting and the Gut Microbiota: Mechanisms Linking Microbial Remodeling to Metabolic and Immune Regulation.Nutrients · 2026Review
- Remodelling of the gut virome after long-term fasting.NPJ biofilms and microbiomes · 2026Article
- How nutrient starvation impacts the gut microbiome.Nature microbiology · 2025Review
- Impact of Prolonged Fasting on the Oral Microbiome in Patients With Metabolic Syndrome: An Exploratory Secondary Analysis.Journal of clinical periodontology · 2025Article
- Intermittent fasting and metabolic dysfunction-associated steatotic liver disease: the potential role of the gut-liver axis.Cell & bioscience · 2025Review
- Long-term fasting induces a remodelling of fatty acid composition in erythrocyte membranes.European journal of clinical investigation · 2025Article
- Fasting elicits gut microbiome signature changes that extend to type 1 diabetes patients.Frontiers in endocrinology · 2025Article
- Case Report: Sustained weight loss and glycemic control from repeated long-term fasting in type 2 diabetes.Frontiers in clinical diabetes and healthcare · 2025Article
- Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.Frontiers in systems biology · 2025Article
- Revisiting the (anti)inflammatory effects of prolonged fasting: the importance of baseline-dependent responses.Frontiers in nutrition · 2025Article
- Effects of Long-Term Fasting on Gut Microbiota, Serum Metabolome, and Their Association in Male Adults.Nutrients · 2024Article
- Impact of Long-term Fasting on Breath Volatile Sulphur Compounds, Inflammatory Markers and Saliva Microbiota Composition.Oral health & preventive dentistry · 2024Article
- Fasting in Science and Clinics: A Report on Proceedings from the International Scientific Symposium and Conference on Fasting in Berlin (June 2023).Complementary medicine research · 2024Review
- Intermittent fasting modulates human gut microbiota diversity in a phenotype-dependent manner: a systematic review.Bioscience of microbiota, food and health · 2024Review
- The Beneficial Effects of Dietary Interventions on Gut Microbiota-An Up-to-Date Critical Review and Future Perspectives.Nutrients · 2023Review
- Review
- Article
- Intestinal Microbiota Reduction Followed by Fasting Discloses Microbial Triggering of Inflammation in Rheumatoid Arthritis.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fasting is increasingly popular to manage metabolic and inflammatory diseases. Despite the role that the human gut microbiota plays in health and diseases, little is known about its composition and functional capacity during prolonged fasting when the external nutrient supply is reduced or suppressed. We analysed the effects of a 10-d periodic fasting on the faecal microbiota of fifteen healthy men. Participants fasted according to the peer-reviewed Buchinger fasting guidelines, which involve a daily energy intake of about 1046 kJ (250 kcal) and an enema every 2 d. Serum biochemistry confirmed the metabolic switch from carbohydrates to fatty acids and ketones. Emotional and physical well-being were enhanced. Faecal 16S rRNA gene amplicon sequencing showed that fasting caused a decrease in the abundance of bacteria known to degrade dietary polysaccharides such as Lachnospiraceae and Ruminococcaceae. There was a concomitant increase in Bacteroidetes and Proteobacteria (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.