Evidence map›Paper›PMID 31798848›Full record

ArticleLight, science & applications2019

MATRIEX imaging: multiarea two-photon real-time in vivo explorer.

Mengke Yang, Zhenqiao Zhou, Jianxiong Zhang, Shanshan Jia, Tong Li, Jiangheng Guan, Xiang Liao, Bing Leng, Jing Lyu, Kuan Zhang and 12 more

Abstract read
In one paragraph

Article in Light, science & applications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Mengke Yang1Key Laboratory of Optical System Advanced Manufacturing Technology, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033 China.
Zhenqiao Zhou3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.
Jianxiong Zhang4Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038 China.
Shanshan Jia4Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038 China.
Tong Li4Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038 China.
Jiangheng Guan4Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038 China.
Xiang Liao5Center for Neurointelligence, Chongqing University, Chongqing, 401331 China.ORCID 0000-0001-6324-5206
Bing Leng3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.
Jing Lyu3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.
Kuan Zhang4Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038 China.
Min Li3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.
Yan Gong3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.
Zhiming Zhu6Center for Hypertension and Metabolic Diseases, Daping Hospital, Chongqing, 400042 China.
Junan Yan7Advanced Institute of Brain and Intelligence, Guangxi University, Nanning, 530005 China.
Yi Zhou7Advanced Institute of Brain and Intelligence, Guangxi University, Nanning, 530005 China.
Jian K Liu8Centre for Systems Neuroscience, Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK.
Zsuzsanna Varga9Institute of Neuroscience, Technical University Munich, 80802 Munich, Germany.
Arthur Konnerth9Institute of Neuroscience, Technical University Munich, 80802 Munich, Germany.
Yuguo Tang3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.
Jinsong Gao1Key Laboratory of Optical System Advanced Manufacturing Technology, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033 China.
Xiaowei Chen4Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038 China.
Hongbo Jia3Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 China.ORCID 0000-0003-1585-2161

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two-photon laser scanning microscopy has been extensively applied to study in vivo neuronal activity at cellular and subcellular resolutions in mammalian brains. However, the extent of such studies is typically confined to a single functional region of the brain. Here, we demonstrate a novel technique, termed the multiarea two-photon real-time in vivo explorer (MATRIEX), that allows the user to target multiple functional brain regions distributed within a zone of up to 12 mm in diameter, each with a field of view (FOV) of ~200 μm in diameter, thus performing two-photon Ca

Indexed as

Ca2+ imagingMultiphoton microscopy

Identifiers

PMID31798848
PMCPMC6881438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.