ArticleLight, science & applications2019
Super-resolution localization photoacoustic microscopy using intrinsic red blood cells as contrast absorbers.
Article in Light, science & applications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 201 citations in OpenAlex.
- Article
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- Robust automated three-dimensional speed-of-sound compensation for hemispherical photoacoustic computed tomography.Photoacoustics · 2026Article
- Electrically switchable dual-focus metalens for depth-extended in vivo photoacoustic imaging of ophthalmic vascular disease.Light, science & applications · 2026Article
- Ultrasound-guided sound speed correction for photoacoustic computed tomography.Photoacoustics · 2026Article
- Super-resolution functional photoacoustic microscopy via label-free cell tracking.Light, science & applications · 2026Article
- Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Dual-channel high-speed functional photoacoustic microscopy with ultra-wide field of view.Light, science & applications · 2026Article
- Label-free photoacoustic imaging of glassfrog development.Photoacoustics · 2025Article
- Clinical ultrasound, photoacoustic, and fluorescence image-guided lymphovenous anastomosis microsurgery via a transparent ultrasound transducer array.Nature communications · 2025Article
- A cortex-wide multimodal microscope for simultaneous CaNature communications · 2025Article
- Imaging the brain by traversing the skull with light and sound.Nature biomedical engineering · 2025Review
- Light in, sound keys out: photoacoustic PUFs from stochastic nanocomposites.Nature communications · 2025Article
- A comprehensive review of high-performance photoacoustic microscopy systems.Photoacoustics · 2025Review
- Wavelength-time-division multiplexed fiber-optic sensor array for wide-field photoacoustic microscopy.Photoacoustics · 2025Article
- Article
- Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting.Photoacoustics · 2025Article
- All-fiber three-wavelength laser for functional photoacoustic microscopy.Photoacoustics · 2025Article
- Wide-Field High-Speed Scanning Acoustic/Photoacoustic Microscopy for Whole-Body Imaging of Small Animals.Biosensors · 2025Article
- Optoacoustic lenses for lateral sub-optical resolution elasticity imaging.Photoacoustics · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photoacoustic microscopy (PAM) has become a premier microscopy tool that can provide the anatomical, functional, and molecular information of animals and humans in vivo. However, conventional PAM systems suffer from limited temporal and/or spatial resolution. Here, we present a fast PAM system and an agent-free localization method based on a stable and commercial galvanometer scanner with a custom-made scanning mirror (L-PAM-GS). This novel hardware implementation enhances the temporal resolution significantly while maintaining a high signal-to-noise ratio (SNR). These improvements allow us to photoacoustically and noninvasively observe the microvasculatures of small animals and humans in vivo. Furthermore, the functional hemodynamics, namely, the blood flow rate in the microvasculature, is successfully monitored and quantified in vivo. More importantly, thanks to the high SNR and fast B-mode rate (500 Hz), by localizing photoacoustic signals from captured red blood cells without any contrast agent, unresolved microvessels are clearly distinguished, and the spatial resolution is improved by a factor of 2.5 in vivo. L-PAM-GS has great potential in various fields, such as neurology, oncology, and pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.