Evidence map›Paper›PMID 31798780›Full record

ArticleWorld journal of gastrointestinal oncology2019

Toll-like receptor 9 polymorphisms and

Manoela Dias Susi, de Matos Lourenço Caroline, Lucas Trevizani Rasmussen, Spencer Luis Marques Payão, Ana Flávia Teixeira Rossi, Ana Elizabete Silva, Juliana Garcia de Oliveira-Cucolo

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Signaling pathways and targeted interventions for precancers.Signal transduction and targeted therapy · 2026
    Review
  4. Impact ofBiomolecules & biomedicine · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Innate immunity - the hallmark ofWorld journal of clinical cases · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Manoela Dias SusiDepartment of Graduate-Level Research, USC-Sacred Heart University, Bauru 17011-970, SP, Brazil.
de Matos Lourenço CarolineDepartment of Graduate-Level Research, USC-Sacred Heart University, Bauru 17011-970, SP, Brazil.
Lucas Trevizani RasmussenDepartment of Genetics and Molecular Biology, FAMEMA-Marilia Medical School, Marília 17519-030, SP, Brazil.
Spencer Luis Marques PayãoDepartment of Genetics and Molecular Biology, FAMEMA-Marilia Medical School, Marília 17519-030, SP, Brazil.
Ana Flávia Teixeira RossiDepartment of Biology, São Paulo State University-UNESP, São José do Rio Preto 15054-000, SP, Brazil.
Ana Elizabete SilvaDepartment of Biology, São Paulo State University-UNESP, São José do Rio Preto 15054-000, SP, Brazil. ae.silva@unesp.br.
Juliana Garcia de Oliveira-CucoloDepartment of Molecular, Biological and Genetics and Molecular Biology Research Unit - UPGEM, Faculty of Medicine of São José do Rio Preto - FAMERP, São José do Rio Preto 15090-000, SP, Brazil.
Faculdade de Medicina de Marília · BRUniversity of The Sacred Heart · PRCentro Universitário de Rio Preto · BRFaculdade de Medicina de São José do Rio Preto · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToll-like receptors (TLRs) are the first line of host defense, and are involved in

aimTo evaluate whether TLR9 rs5743836 and rs187084 SNPs contribute to the risk of gastric carcinogenesis, and its influence on mRNA expression.

methodsA case-control study was conducted to evaluate two TLR9 SNPs (TLR9

resultsFor TLR9

conclusionOur findings show that TLR9 rs5743836 and rs187084 polymorphisms are associated with a higher risk of carcinogenesis gastric, and that TLR9 mRNA levels can be modulated by TLR9-1237 TC + CC variant genotypes and

Indexed as

Chronic gastritisGastric cancerGene expressionHelicobacter pyloriPolymorphismsToll-like receptor 9

Identifiers

PMID31798780
PMCPMC6883180
OpenAlexW2983100789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.