Evidence map›Paper›PMID 31798697›Full record

ArticleExperimental and therapeutic medicine2019

Long non-coding RNA PRNCR1 has an oncogenic role in breast cancer.

Qian Guo, Shuang Lv, Bingping Wang, Yinbing Li, Nier Cha, Ruigang Zhao, Wenhua Bao, Baoqing Jia

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Association of lncRNAJournal of genetics · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qian GuoBreast Neoplasms Surgical Department, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Shuang LvDepartment of Oncology, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Bingping WangOncology Institute, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Yinbing LiBreast Neoplasms Surgical Department, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Nier ChaBreast Neoplasms Surgical Department, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Ruigang ZhaoBreast Neoplasms Surgical Department, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Wenhua BaoBreast Neoplasms Surgical Department, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Baoqing JiaBreast Neoplasms Surgical Department, Inner Mongolia People's Hospital, Huhehot, Inner Mongolia 010010, P.R. China.
Inner Mongolia People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have important roles in the development and progression of various types of human cancer. However, the expression and function of the lncRNA prostate cancer-associated non-coding RNA 1 (PRNCR1) in breast cancer remains unclear. Reverse transcription-quantitative PCR was performed to measure the levels of mRNA expression. Cell counting kit-8, flow cytometry, wound healing and Transwell assays were also performed to study cell proliferation, cell cycle, migration and invasion, respectively. The results of the present study revealed that PRNCR1 expression levels were higher in breast cancer tissues compared with adjacent normal tissues in a patient study. It was also determined that high expression of PRNCR1 was significantly associated with advanced clinical stage, positive metastasis and poor prognosis for patients with breast cancer.

Indexed as

breast cancerlong non-coding RNAprostate cancer-associated non-coding RNA 1

Identifiers

PMID31798697
PMCPMC6878908
OpenAlexW2982413348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.