Evidence map›Paper›PMID 31798650›Full record

ArticleJournal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent2019

Effectiveness of an Integrated Care Pathway for Adolescents with Depression: A Pilot Clinical Trial Protocol.

Darren B Courtney, Amy Cheung, Joanna Henderson, Kathryn Bennett, Marco Battaglia, John Strauss, Rachel Mitchell, Karen Wang, Peter Szatmari

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PubMed Full text at PMC
In one paragraph

Article in Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Darren B CourtneyCentre for Addiction and Mental Health (CAMH), Assistant Professor, University of Toronto, Toronto, Ontario.
Amy CheungSunnybrook Health Sciences Centre, Associate Professor, University of Toronto, Toronto, Ontario.
Joanna HendersonCentre for Addiction and Mental Health (CAMH), Associate Professor, University of Toronto, Toronto Ontario.
Kathryn BennettProfessor, Health Research Methods, Evidence and Impact (formerly Clinical Epidemiology and Biostatistics), McMaster University, Hamilton, Ontario.
Marco BattagliaCentre for Addiction and Mental Health (CAMH), Associate Professor, University of Toronto, Toronto, Ontario.
John StraussCentre for Addiction and Mental Health (CAMH), Associate Professor, University of Toronto, Toronto, Ontario.
Rachel MitchellSunnybrook Health Sciences Centre, Assistant Professor, University of Toronto, Toronto, Ontario.
Karen WangSunnybrook Health Sciences Centre, Assistant Professor, University of Toronto, Toronto, Ontario.
Peter SzatmariCentre for Addiction and Mental Health (CAMH), Hospital for Sick Children, Professor, University of Toronto, Toronto, Ontario.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur group aims to improve treatment response for adolescents with depression through the use of an Integrated Care Pathway (ICP) we developed using: (1) recommendations from a high quality Clinical Practice Guideline (CPG); and, (2) a measurement-based care framework.

methodPre-specified criteria will identify eligible adolescents in two outpatient hospital study sites. Study group allocation, to the ICP versus treatment as usual (TAU), is based on site of presentation. The primary clinical outcome is reduction of depression symptoms, assessed using the Childhood Depression Rating Scale - Revised (CDRS-R). Measures will be taken at baseline and every four weeks until 20 weeks of treatment has been offered.

resultsOur overall hypothesis is that the ICP will be associated with greater improvement in depressive symptoms compared to TAU. Feasibility targets for this pilot trial include the following: recruitment of 30 participants per site over a 21-month period, 95% baseline assessment completion rates, 90% clinician adherence to the ICP in the intervention arm and 80% completion of the scheduled CDRS-R measures over the 20-week interval. Focus-group feedback from youth and parents will also produce qualitative information.

conclusionsIf feasibility targets are met, and preliminary results regarding clinical outcomes are promising, then a multi-center cluster RCT would be pursued.

Indexed as

adolescentdepressionintegrated care pathwaymeasurement-based carepilot study

Identifiers

PMID31798650
PMCPMC6863574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.