ArticleFrontiers in genetics2019
Transcriptome Analysis Identifies Candidate Genes and Pathways Associated With Feed Efficiency in Hu Sheep.
Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Metabolic and muscular adaptations to dietary succinate in Tan sheep: Insights from transcriptomics.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- First breed-pool whole genome sequencing of egyptian sheep: a comprehensive genomic atlas revealing diversity and candidate genes for production and adaptation.BMC biotechnology · 2026Article
- TIAM2 and ADCY7 polymorphisms and their association with feed efficiency in Huaibei partridge chickens.Poultry science · 2026Article
- Complementary structure of statistical significance and predictive relevance in explainable machine learning-based transcriptomic tissue classification of Hanwoo cattle.Frontiers in genetics · 2026Article
- Genome-wide cis-expression Quantitative Trait Loci (eQTL) and transcriptomic signals reveal distinct molecular regulation across correlated feed efficiency traits.Frontiers in genetics · 2026Article
- A Functional Regulatory Variant ofAnimals : an open access journal from MDPI · 2025Article
- Application of multi-omics technology in pathogen identification and resistance gene screening of sheep pneumonia.BMC genomics · 2025Article
- Insights into garlic (Allium Sativum)'s nutrigenomics-associated fly-repellent potency in cattle.Tropical animal health and production · 2025Review
- Integration of epigenomic and genomic data to predict residual feed intake and the feed conversion ratio in dairy sheep via machine learning algorithms.BMC genomics · 2025Article
- Multi-omics revealed the mechanism of feed efficiency in sheep by the combined action of the host and rumen microbiota.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Integrated multi-omics reveals the relationship between growth performance, rumen microbes and metabolic status of Hu sheep with different residual feed intakes.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Genes involved in the cholecystokinin receptor signaling map were differentially expressed in the jejunum of steers with variation in residual feed intake.Veterinary and animal science · 2024Article
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- Article
- Analysis of liver miRNA in Hu sheep with different residual feed intake.Frontiers in genetics · 2023Article
- Feed efficiency in dairy sheep: An insight from the milk transcriptome.Frontiers in veterinary science · 2023Article
- Identification and characterization of circular RNAs in association with the feed efficiency in Hu lambs.BMC genomics · 2022Article
- Transcriptome analysis reveals the potential roles of long non-coding RNAs in feed efficiency of chicken.Scientific reports · 2022Article
- Review
- Polymorphisms inFrontiers in veterinary science · 2022Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the genetic improvement of livestock and poultry, residual feed intake (RFI) is an important economic trait. However, in sheep, the genetic regulatory mechanisms of RFI are unclear. In the present study, we measured the feed efficiency (FE)-related phenotypes of 137 male Hu lambs, and selected six lambs with very high (n = 3) and very low (n = 3) RFI values and analyzed their liver transcriptomes. A total of 101 differentially expressed genes were identified, of which 40 were upregulated and 61 were downregulated in the low-RFI group compared with that in the high-RFI group. The downregulated genes were mainly concentrated in immune function pathways, while the upregulated genes were mainly involved in energy metabolism pathways. Two differentially expressed genes,
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