ArticleIndian journal of nephrology
Heavy Metals and Pesticides in Chronic Kidney Disease - Results from a Matched Case-Control Study from a Rural Population in Shivamogga District in South India.
Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Heterogeneity in diagnostic criteria for chronic kidney disease of undetermined etiology (CKDu): a systematic review of the literature.BMC nephrology · 2025Pooled it
- Impact of an educational intervention model on pesticide practices among farmers: a randomized controlled trial protocol.BMC public health · 2026Article
- Exploring the Association Between Potentially Toxic Elements and Chronic Kidney Disease of Unknown Etiology in Eastern Uttar Pradesh, India.Biological trace element research · 2026Article
- Assessment of prevalence and risk factors of chronic kidney disease in A. Konduru tribal region of Andhra Pradesh, India: A cross-sectional study.Journal of family medicine and primary care · 2025Article
- Environmental factors and chronic kidney disease: a case-control study.Scientific reports · 2024Article
- Exposome and Metabolome Analysis of Sugarcane Workers Reveals Predictors of Kidney Injury.Kidney international reports · 2024Article
- The association between urinary metals/metalloids and chronic kidney disease among general adults in Wuhan, China.Scientific reports · 2023Article
- Chronic kidney disease of unknown etiology in India: a comparative study with Mesoamerican and Sri Lankan nephropathy.Environmental science and pollution research international · 2022Review
- Pesticide Levels and Other Etiopathogenetic Factors in Patients with Chronic Kidney Disease of Unknown Cause in Central India - A Case-Control Study.Indian journal of nephrologyArticle
- Prevalence of Chronic Kidney Disease and its Association with Pesticide Exposure in Bargarh District, Odisha, India.Indian journal of nephrologyArticle
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3 authors at 2 institutions in 1 country.
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Abstract
introductionThere is a high prevalence of chronic kidney disease (CKD) in the rural agrarian population of South India and it often appears unrelated to major known causes such as diabetes or glomerulonephritis.
methodsIn a matched case-control study conducted in a rural population in Shivamogga district in South India, the association of heavy metals - lead (Pb), arsenic (As), cadmium (Cd) - and pesticides in CKD was studied. Blood and spot urine samples were tested quantitatively for heavy metals and qualitatively for pesticides.
resultsIn all, 69 matched pairs (40 female, 58%) were recruited. The mean estimated glomerular filtration rate (mL/min/1.73 m2) was 60.1 (14.2) in cases and 83.4 (13.4) in controls. Elevated blood lead level >5 μg/dL was seen in 15 cases and 25 controls, respectively [P = 0.035, matched odds ratio (MOR) 0.5, 95% confidence interval (CI) 0.22-1.05]. Urinary Pb was elevated in 16 cases and 13 controls, respectively (
conclusionsThere was no statistical significant association between any of the studied heavy metals and CKD, although there was a significant burden of heavy metals in the studied subjects.
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