ArticleScientific reports2019
The role of CRP and Pentraxin 3 in the prediction of systemic inflammatory response syndrome and death in acute pancreatitis.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- The impact of fluid resuscitation via colon on patients with severe acute pancreatitis.Scientific reports · 2021Trial
- Insight to Neglected Biomarkers in COVID-19: A Comprehensive Narrative Review".Biomarker insights · 2026Review
- Development of a prediction method for severe pancreatitis using a nomogram.Frontiers in medicine · 2026Article
- Automated machine learning for early prediction of systemic inflammatory response syndrome in acute pancreatitis.BMC medical informatics and decision making · 2025Article
- A case-control prospective study to unravel zinc alpha 2 glycoprotein role in the pathophysiology of diabetic retinopathy.International ophthalmology · 2025Article
- Article
- Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection.Nature communications · 2024Article
- Progress in the study of pentraxin-3(PTX-3) as a biomarker for sepsis.Frontiers in medicine · 2024Review
- Pentraxin 3, a serum biomarker in human T-cell lymphotropic virus type-1-associated myelopathy patients and asymptomatic carriers.Medical microbiology and immunology · 2023Article
- Current trends in acute pancreatitis: Diagnostic and therapeutic challenges.World journal of gastroenterology · 2023Review
- Increased Levels of serum Pentraxin 3 in Critical Coronavirus Disease-2019 Patients.Environmental science and pollution research international · 2022Article
- Article
- Negative Regulators of Inflammation Response to the Dynamic Expression of Cytokines in DF-1 and MDCK Cells Infected by Avian Influenza Viruses.Inflammation · 2022Article
- Dynamic Changes in Pentraxin-3 and Neprilysin in ST Segment Elevation Myocardial Infarction.Biomedicines · 2022Article
- Mean corpuscular hemoglobin predicts the length of hospital stay independent of severity classification in patients with acute pancreatitis.Open medicine (Warsaw, Poland) · 2022Article
- A nomogram based on serum cystatin C for predicting acute kidney injury in patients with traumatic brain injury.Renal failure · 2021Observational
- Small Incision Combined with Nephroscope Operation in the Treatment of Infectious Pancreatic Necrosis: A Single-Center Experience of 37 Patients.Gastroenterology research and practice · 2021Article
- Incidence and Burden of Acute Kidney Injury among Traumatic Brain-Injury Patients.Risk management and healthcare policy · 2021Article
- Clinical features in 52 patients with COVID-19 who have increased leukocyte count: a retrospective analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Fibroblast Growth Factor (FGF) Signaling Protects Against Acute Pancreatitis-Induced Damage by Modulating Inflammatory Responses.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pentraxin 3 (PTX3) is an acute phase protein. Our goal was to assess PTX3 as a predictor of systemic inflammatory response syndrome (SIRS), death and disease severity in acute pancreatitis (AP) in comparison to C-reactive protein (CRP) and the APACHE II score. From April 2011 to January 2015, 142 patients with AP were included in this single center post hoc analysis of prospectively collected data at the University Hospital Basel, Switzerland. Disease severity was rated by the revised Atlanta criteria (rAC). Inflammatory response was measured by the SIRS criteria. PTX3, CRP and APACHE II score were measured. Patients median PTX3 plasma concentrations in AP were higher in moderate (3.311 ng/ml) and severe (3.091 ng/ml) than in mild disease (2.461 ng/ml). Overall, 59 occurrences of SIRS or death were observed. In the prediction of SIRS or death, PTX3 was inferior to CRP and APACHE II, with modest predictive discriminatory ability of all three markers and AUC of 0.54, 0.69 and 0.69, respectively. Upon combination of CRP with PTX3, AUC was 0.7. PTX3 seems to be inferior to CRP and APACHE II in the prediction of SIRS or death in AP and does not seem to improve the predictive value of CRP upon combination of both parameters.
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